By Medically reviewed by Hello Doktor Medical Panel


What is Novalgin® (metamizole) used for?

Novalgin® is commonly used for many different types of pain such as tumors pain, pain after surgery or injuries. It can also be given when other forms of treatment do not propose any effect. Novalgin® is not used for treatment of mild pain (toothache, headache, menstrual pain).

How should I take Novalgin® (metamizole)?

Taking Novalgin® followings directions in patient leaflet or of your doctor, including:

  • You should swallow the tablets as a whole.
  • Do not crush or chew it.
  • You should take Novalgin ®with a glass of water.

How do I store Novalgin® (metamizole)?

Novalgin® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Novalgin® in the bathroom or the freezer. There may be different brands of Novalgin® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Novalgin® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Novalgin® (metamizole)?

Before using Novalgin®, tell your doctor if:

  • You have allergies to Novalgin®, excipients using for dosage form containing Novalgin®.
  • You have allergies to any other medicines, foods, dyes, preservatives, or animals.
  • You have any other health conditions.

Novalgin® should not be used in children under 6 years of age without direction of a doctor.

Is it safe during pregnancy or breastfeeding?


Novalgin® should not be used during pregnancy, especially during the first 12 weeks and last 12 weeks because it may damage unborn baby.


Avoid breastfeeding while you are using Novalgin®. After you stop using the medicine, it takes at least two days, to set off again to breastfeed.

Side effects

What side effects can occur from Novalgin® (metamizole)?

Novalgin® can cause the side effects. These are:

  • Nausea
  • Vomiting
  • Diarrhea
  • Pain and discomfort in the stomach
  • Drowsiness
  • Nervousness
  • Headache
  • Dizziness
  • Blood in the urine, change in color of urine
  • Skin rash
  • Itching
  • Swelling
  • Shortness of breath
  • Cold sweat drenching and others
  • Anemia
  • Agranulocytosis
  • Fever
  • Fatigue
  • Difficulty swallowing
  • Dry mouth
  • Decreased blood pressure

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Novalgin® (metamizole)?

Novalgin® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

These following medicines should be alerted to your doctor:

  • Penicillin
  • Metformin
  • Glimepiride
  • Gliclazide
  • Glipizide
  • Warfarin (Farin)
  • Heparin
  • Nadroparin (Fraxiparin)
  • Prednisone
  • Methyl prednisolone
  • Dexamethasone
  • Methotrexate

Does food or alcohol interact with Novalgin® (metamizole)?

Do not apply tobacco and alcohol while you are on therapy with Novalgin®, because of the increased risk of side effects.

What health conditions may interact with Novalgin® (metamizole)?

Novalgin may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, especially:

  • Trouble breathing (such as asthma)
  • Bone marrow damage
  • Genetic conditions, such as lack of certain enzymes (e.g., glucose 6 phosphate dehydrogenase)
  • Anemia
  • Liver or kidney damage
  • Ulcer in the stomach or duodenum
  • Cardiovascular disease (increased or decreased blood pressure, angina pectoris, heart failure, history of myocardial infarction or stroke)


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.

What is the dose of Novalgin® (metamizole) for an adult?

The usual dosage is Novalgin® 500 mg up to 1000 mg several times a day. The maximum daily dose is 5000 mg. The duration of treatment should not be more than 5 days.

What is the dose of Novalgin® (metamizole) for a child?

For children aged more than 15

Your child should take 1-2 tablets up to 4 times a day (no more than 8 tablets a day).

A dose of 25-50 drops, up to 4 times a day (no more than 200 drops a day) can be prescribed  for child aged more than 15.

For neonates aged from 3 to 11 months:

The recommended dose is 2-6 drops up to 4 times a day.

For children aged from 1 to 3 years:

The recommended dose is 4-12 drops up to 4 times a day.

For children aged from 4 to 6 years:

The recommended dose is 6-19 drops up to 4 times a day.

For children aged from 7 to 9 years:

The recommended dose is 10-25 drops up to 4 times a day.

For children aged from 10 to 12 years:

The recommended dose is 12-37 drops up to 4 times a day.

For children aged from 13 to 14 years:

The recommended dose is 19-44 drops up to 4 times a day.

How is Novalgin® (metamizole) available?

Novalgin® is available in the following dosage forms and strengths: ampoules and tablets.

  • Tablet: 250 – 500 mg
  • Oral drop solution: 500 mg/ml

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

Symptoms of overdose include nausea, vomiting, headache, dizziness, fainting, heart rate disturbance, kidney damage, and others.

What should I do if I miss a dose?

If you miss a dose of Novalgin®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: February 18, 2017 | Last Modified: December 19, 2019

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