No Spa

By Medically reviewed by Hello Doktor Medical Panel


What is No-spa® (drotaverine hydrochloride) used for?

No-spa® is commonly used for smooth muscle spasms connected with diseases of biliary origin: cholecystolithiasis, cholangiolithiasis, cholecystopathy, cholecystitis, pericholecystitis, cholangitis papillitis. Also, it used to treat smooth muscle spasms of the urinary tract: nephrolithiasis, ureterolithiasis, pyelitis, cystitis, vesical tenesmus.

  • Smooth muscle spasms of gastrointestinal origin: gastric and duodenal ulcer, enteritis, colitis and pylorus spasm, irritable colon syndrome, spastic constipation or gas syndrome, pancreatitis.
  • Headaches of vascular origin.
  • In gynecological diseases: dysmenorrhoea, adnexitis.

How should I take No-spa® (drotaverine hydrochloride)?

  • No-spa® may be taken with or without food.
  • Tell doctor if you have severe renal/hepatic/cardiac dysfunction and porphyria.
  • Tell doctor if you are hypersensitive to the active ingredient or to any of the excipient.
  • Tell your doctor if you have severe cardiac insufficiency (low output syndrome).

How do I store No-spa® (drotaverine hydrochloride)?

No-spa® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store No-spa® in the bathroom or the freezer. There may be different brands of No-spa® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush No-spa® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using No-spa® (drotaverine hydrochloride)?

You should not use this medicine, if:

  • You are hypersensitive to drotaverine hydrochloride or to any excipients.
  • You have impaired liver, kidney or severe heart.
  • In children under 6.

This drug should be used with caution:

  • In patients with hypotension.
  • Patients with lactose intolerance stemming in tablets can cause gastrointestinal.
  • In children under 6.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using No-spa® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking No-spa®. No-spa® is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk;
  • B=No risk in some studies;
  • C=There may be some risk;
  • D=Positive evidence of risk;
  • X=Contraindicated;
  • N=Unknown.

Side effects

What side effects can occur from No-spa® (drotaverine hydrochloride)?

Some side effect could occur when you use No-spa®:

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with No-spa® (drotaverine hydrochloride)?

No-spa® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects, such as:

  • Levodopa;
  • Fanalgesics;
  • Antimuscarinics or benzodiazepines.

To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with No-spa® (drotaverine hydrochloride)?

No-spa® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with No-spa® (drotaverine hydrochloride)?

No-spa® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using No-spa® (drotaverine hydrochloride).

What is the dose of No-spa® (drotaverine hydrochloride) for an adult?

Oral: 120-240mg daily (in 2-3 divided doses).

What is the dose of No-spa® (drotaverine hydrochloride) for a child?

Children between 1 – 6 years: the usual daily dose is 40-120 mg (in 2-3 divided doses).

Children over 6 years: the usual daily dose is 80-200mg (in 2-5 divided doses).

How is No-spa® (drotaverine hydrochloride) available?

No-spa® is available in the following dosage forms and strengths:

  • No-Spa 40mg tablets.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services (115) or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of No-spa®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: November 23, 2016 | Last Modified: December 19, 2019

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