By Medically reviewed by Hello Doktor Medical Panel


What is Rigevidon® (levonorgestrel, ethinyl estradiol) used for?

Rigevidon® is commonly used for oral contraception.

It may be prescribed for other uses; ask your doctor or pharmacist for more information.

How should I take Rigevidon® (levonorgestrel, ethinyl estradiol)?

  • Do not crush, break, or chew the tablets.
  • Swallow Rigevidon® whole with a glass of water.

Ask your health care provider any questions you may have about how to use Rigevidon®.

How do I store Rigevidon® (levonorgestrel, ethinyl estradiol)?

Rigevidon® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Rigevidon® in the bathroom or the freezer. There may be different brands of Rigevidon® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Rigevidon® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Rigevidon® (levonorgestrel, ethinyl estradiol)?

Consult with your doctor or pharmacist, if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Rigevidon® or other medications.
  • You have any other types of allergies, such as to foods, dyes, preservatives, or animals.

Is it safe during pregnancy or breastfeeding?


There are no adequate studies in women for determining risk when using this medication during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication. This medication is pregnancy risk category X, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown


Rigevidon® should not be taken during breastfeeding.

Always consult your health care provider prior to using Rigevidon® if you are pregnant, breastfeeding.

Side effects

What side effects can occur from Rigevidon® (levonorgestrel, ethinyl estradiol)?

Rigevidon® may cause these side effects, such as:

  • Intermenstrual bleeding, changes in vaginal discharge, vaginal infections (e.g., candidiasis)
  • Aggravation of endometriosis
  • Breast tenderness
  • Nausea
  • Vomiting
  • Cholelithiasis
  • Cholestatic jaundice
  • Hepatitis
  • Thrombosis
  • Chloasma
  • Erythema nodosum
  • Rash
  • Problems with wearing contact lenses
  • Headache or migraine
  • Mood changes
  • Unusual fatigue
  • Fluid retention
  • Decreased glucose tolerance
  • Changes in libido

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side effect, please consult your doctor or pharmacist.


What drugs may interact with Rigevidon® (levonorgestrel, ethinyl estradiol)?

Rigevidon® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Rigevidon® may cause interaction with these below medications, such as:

  • Hepatic enzyme inducers
  • Antibiotics
  • Dihydroergotamine
  • Tranquilizers
  • Coumarin- or indandione-containing anticoagulants
  • Tricyclic antidepressants
  • Maprotiline
  • Oral antidiabetics
  • Insulin
  • Activated charcoal
  • Laxatives
  • Bromocriptine
  • Hepatotoxic drugs

Does food or alcohol interact with Rigevidon® (levonorgestrel, ethinyl estradiol)?

Rigevidon® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Rigevidon® (levonorgestrel, ethinyl estradiol)?

Rigevidon® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, especially:

  • Cardiac insufficiency
  • Renal impairment
  • Obesity
  • Gallstones
  • Asthma
  • Depression
  • Epilepsy
  • Migraine
  • Severe varicose veins
  • Phlebitis
  • Sclerosis multiplex
  • Chorea minor
  • Latent tetany
  • Benign uterine tumor
  • Endometriosis or mastopathia
  • Family history of juvenile thromboembolic diseases or blood coagulation disorders
  • Infectious hepatitis


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.

What is the dose of Rigevidon® (levonorgestrel, ethinyl estradiol) for an adult?

1 tablet daily for 21 days from the first day of the cycle, followed by 7 tablets-free days.

What is the dose of Rigevidon® (levonorgestrel, ethinyl estradiol) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Rigevidon® (levonorgestrel, ethinyl estradiol) available?

Rigevidon® is available in the following dosage forms and strengths:

  • Rigevidon® Coated Tablet: Levonorgestrel 150 mcg, ethinyl estradiol 30 mcg.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

It is also important to carry a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking with you in case of emergencies.

What should I do if I miss a dose?

If you miss a dose of Rigevidon®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: December 15, 2016 | Last Modified: December 19, 2019

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