By Medically reviewed by Panel Perubatan Hello Doktor


What is Nissel® (biphenyl dimethyl dicarboxylate) used for?

Nissel® supports treatment hepatitis due to virus or chemicals (especially antituberculosis drugs).

How should I take Nissel® (biphenyl dimethyl dicarboxylate)?

It comes as a capsule to take by mouth, with food.

How do I store Nissel® (biphenyl dimethyl dicarboxylate)?

Nissel® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Nissel® in the bathroom or the freezer. There may be different brands of Nissel® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Nissel® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Nissel® (biphenyl dimethyl dicarboxylate)?

Before using this drug, tell your doctor if you have:

  • History of liver
  • Gallbladder
  • Pancreas
  • Bile duct disorders
  • Pregnancy and breastfeeding

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Nissel® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Nissel®.

Side effects

What side effects can occur from Nissel® (biphenyl dimethyl dicarboxylate)?

When using Nissel®, side effects can occur:

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Nissel® (biphenyl dimethyl dicarboxylate)?

Nissel® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Nissel® (biphenyl dimethyl dicarboxylate)?

Nissel® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Nissel® (biphenyl dimethyl dicarboxylate)?

Nissel® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Nissel® (biphenyl dimethyl dicarboxylate).

What is the dose of Nissel® (biphenyl dimethyl dicarboxylate) for an adult?

Usually administered 1-2 tablets three times daily.
The dose should be appropriately increased according to indication of physician or pharmacist.

What is the dose of Nissel® (biphenyl dimethyl dicarboxylate) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Nissel® (biphenyl dimethyl dicarboxylate) available?

Nissel® is available in the following dosage forms and strengths:

  • Tablet Biphenyl dimethyl dicarboxylate 25 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Nissel®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: January 13, 2017 | Last Modified: December 19, 2019

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