By Medically reviewed by Hello Doktor Medical Panel


What is Dexilant® (dexlansoprazole) used for?

Dexilant® is commonly used for healing and maintaining healing of irritation of the esophagus. It is also used to treat symptoms of gastroesophageal reflux disease (GERD) (e.g., heartburn). It may also be used for other conditions as determined by your doctor.

Dexilant® delayed-release capsules are a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced in the stomach.

How should I take Dexilant® (dexlansoprazole)?

Use Dexilant® delayed-release capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Dexilant® delayed-release capsules come with an extra patient information sheet called a Medication Guide. It also comes with instructions for use. Read them carefully. Read them again each time you get Dexilant® delayed-release capsules refilled.

Take Dexilant® delayed-release capsules by mouth with or without food.

Swallow Dexilant® delayed-release capsules whole. Do not break, crush, or chew before swallowing. If you cannot swallow the capsule whole, you may open it and sprinkle the contents over 1 tablespoon (15 mL) of applesauce. Swallow the entire mixture right away. Do not crush or chew the medicine before swallowing. Do not store the mixture for future use. Read the instructions for use for more information.

You may also open the capsule and sprinkle the contents into 20 mL of water. Use an oral syringe to draw up the mixture. Swirl the mixture and swallow right away. Do not store the mixture for future use. Refill the syringe with water and take to be sure you have taken all the medicine. Follow the instructions for use in the extra patient leaflet.

If the patient is taking Dexilant® delayed-release capsules through a nasogastric tube, follow the instructions for use in the extra patient leaflet.

Continue to take Dexilant® delayed-release capsules even if you feel well. Do not miss any doses.

How do I store Dexilant® (dexlansoprazole)?

Dexilant® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Dexilant® in the bathroom or the freezer. There may be different brands of Dexilant® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Dexilant® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Dexilant® (dexlansoprazole)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Dexilant® or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You have low blood potassium or magnesium levels, low blood vitamin B12 levels or vitamin B12 deficiency, liver problems, or stomach or bowel cancer.
  • You have osteoporosis (weak bones), a family history of osteoporosis, or other risk factors of osteoporosis (e.g., smoking, poor nutrition).
  • You are taking atazanavir, dasatinib, or rilpivirine.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Dexilant® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Dexilant®. Dexilant® is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Dexilant® (dexlansoprazole)?

Check with your doctor if any of these most common side effects persist or become bothersome:

  • Gas
  • Mild diarrhea or stomach pain
  • Nausea
  • Symptoms of upper respiratory tract infection (e.g., cough, runny or stuffy nose, sneezing)
  • Vomiting

Seek medical attention right away if any of these severe side effects occur:

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest or throat; swelling of the mouth, face, lips, or tongue; unusual hoarseness)
  • Bloody or watery stools
  • Bone pain
  • Calf or leg pain, swelling, redness, or tenderness
  • Chest, jaw, or arm pain
  • Depression
  • Fainting
  • Fast, slow, or irregular heartbeat
  • Fever, chills, or sore throat
  • Joint pain, tenderness, swelling, or warmth
  • Red, swollen, blistered, or peeling skin
  • Seizures
  • Severe or persistent diarrhea or stomach pain
  • Severe or persistent nausea or vomiting
  • Shortness of breath
  • Stomach cramps
  • Sudden, severe nausea or vomiting
  • Symptoms of kidney problems (e.g., not able to pass urine, change in the amount of urine produced, blood in the urine, a big weight gain)
  • Symptoms of liver problems (e.g., dark urine, loss of appetite, pale stools, unusual nausea, yellowing of the skin or eyes)
  • Unexplained weight loss
  • Unusual sweating
  • Unusual tiredness or weakness

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Dexilant® (dexlansoprazole)?

Dexilant® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • Diuretics (e.g., furosemide, hydrochlorothiazide) because the risk of low blood magnesium levels may be increased.
  • Anticoagulants (e.g., warfarin), digoxin, methotrexate, saquinavir, or tacrolimus because the risk of their side effects may be increased by Dexilant delayed-release capsules.
  • Ampicillin, atazanavir, bosutinib, clopidogrel, dasatinib, erlotinib, indinavir, iron, itraconazole, ketoconazole, mycophenolate, nelfinavir, nilotinib, posaconazole, rilpivirine, or sorafenib because their effectiveness may be decreased by Dexilant delayed-release capsules.

Does food or alcohol interact with Dexilant® (dexlansoprazole)?

Dexilant® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Dexilant® (dexlansoprazole)?

Dexilant® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Dexilant® (dexlansoprazole).

What is the dose of Dexilant® (dexlansoprazole) for an adult?

Dexilant® Capsules Dosage Regimen by Indication in Patients 12 Years of Age and Older

Healing of EE: One 60 mg capsule once daily, up to 8 weeks.

Maintenance of Healed EE and Relief of Heartburn: One 30 mg capsule once daily. Controlled studies did not extend beyond 6 months in adults and 16 weeks in patients 12 to 17 years of age.

Symptomatic Non-Erosive GERD: One 30 mg capsule once daily. Duration is 4 weeks.

Dexilant® SoluTab Dosage Regimen by Indication in Patients 12 Years of Age and Older

Maintenance of Healed EE and Relief of Heartburn. One 30 mg tablet once daily. Controlled studies did not extend beyond 6 months in adults and 16 weeks in patients 12 to 17 years of age.

Symptomatic Non-Erosive GERD. One 30 mg tablet once daily. Duration is 4 weeks.

What is the dose of Dexilant® (dexlansoprazole) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Dexilant® (dexlansoprazole) available?

Dexilant® is available in the following dosage forms and strengths: dexlansoprazole 30mg

  • Capsule, delayed release; tablet, orally disintegrating, delayed release: dexlansoprazole 30mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room

What should I do if I miss a dose?

If you miss a dose of Dexilant®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: July 26, 2017 | Last Modified: December 19, 2019

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