Update Date 12/05/2020 . 6 mins read


What is Zanocin® (ofloxacin) used for?

Zanocin® is in a class of antibiotics called fluoroquinolones. It works by killing bacteria that cause infections. It is used to treat certain infections including pneumonia, and infections of the skin, bladder, reproductive organs, and prostate (a male reproductive gland).

Zanocin® may also be used to treat bronchitis and urinary tract infections but should not be used for bronchitis and some types of urinary tract infections if other treatments are available.

Zanocin® is also sometimes used to treat other types of infection, including Legionnaires’ disease (type of lung infection), certain sexually transmitted diseases, infections of the bones and joints and of the stomach and intestines. Zanocin® may also be used to treat or prevent anthrax or plague (serious infections that may be spread on purpose as part of a bioterror attack) in people who may have been exposed to the germs that cause these infections in the air. Zanocin® may also be used to treat or prevent travelers’ diarrhea in certain patients. Talk to your doctor about the risks of using Zanocin® to treat your condition.

How should I take Zanocin® (ofloxacin)?

Zanocin® comes as a tablet to take by mouth. It is usually taken with or without food twice a day for 3 days to 6 weeks. The length of treatment depends on the type of infection being treated. Your doctor will tell you how long to take Zanocin®. Take Zanocin® at around the same times every day and try to space your doses 12 hours apart.

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Zanocin® exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Make sure you drink plenty of water or other fluids every day while you are taking Zanocin®.

How do I store Zanocin® (ofloxacin)?

Zanocin® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Zanocin® in the bathroom or the freezer. There may be different brands of Zanocin® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Zanocin® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Zanocin® (ofloxacin)?

Before using this drug, you should know that:

  • Do not drive a car, operate machinery, or participate in activities requiring alertness or coordination until you know how Zanocin® affects you.
  • Tell your doctor and pharmacist if you are allergic or have had a severe reaction to Zanocin®.
  • You should plan to avoid unnecessary or prolonged exposure to sunlight and ultraviolet light (tanning beds and sunlamps) and to wear protective clothing, sunglasses, and sunscreen. Zanocin® may make your skin sensitive to sunlight or ultraviolet light. If your skin becomes reddened, swollen, or blistered, call your doctor.
  • Taking Zanocin® increases the risk that you will develop tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle) during your treatment or for up to several months afterward.
  • Taking Zanocin® may cause changes in sensation and nerve damage that may not go away even after you stop taking Zanocin®.
  • Taking Zanocin® may affect your brain or nervous system and cause serious side effects. This can occur after the first dose of Zanocin®.
  • Taking Zanocin® may worsen muscle weakness in people with myasthenia gravis (a disorder of the nervous system that causes muscle weakness) and cause severe difficulty breathing or death.
  • If you are taking antacids containing aluminum, calcium, or magnesium (Maalox, Mylanta, Tums, others); didanosine (Videx) solution; sucralfate (Carafate); or supplements or multivitamins containing iron or zinc, take Zanocin® 2 hours before or 2 hours after you take these medications.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Zanocin® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Zanocin®.

Side effects

What side effects can occur from Zanocin® (ofloxacin)?

When using this drug, some side effects can occur:

  • Diarrhea
  • Constipation
  • Vomiting
  • Stomach pain or cramps
  • Change in ability to taste food
  • Loss of appetite
  • Dry mouth
  • Excessive tiredness
  • Pale skin
  • Pain, swelling, or itching of the vagina

If you experience any of the following symptoms, or any of the symptoms described in the important warning section, stop taking Zanocin® and call your doctor immediately or get emergency medical help:

  • Severe diarrhea (watery or bloody stools)
  • Rash
  • Hives
  • Itching
  • Peeling or blistering of the skin
  • Fever
  • Swelling of the eyes, face, mouth, lips, tongue, throat, hands, feet, ankles or lower legs
  • Hoarseness
  • Difficulty breathing or swallowing
  • Ongoing or worsening cough
  • Fast or fluttering heartbeat
  • Fainting
  • Loss of consciousness
  • Yellowing of the skin or eyes
  • Light colored stool
  • Dark urine
  • Decreased urination
  • Unusual bruising or bleeding
  • Joint or muscle pain

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Zanocin® (ofloxacin)?

Zanocin® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug, including:

  • Other quinolone or fluoroquinolone antibiotics
  • Gatifloxacin (Tequin)
  • Gemifloxacin (Factive)
  • LevZanocin (Levaquin)
  • Lomefloxacin (Maxaquin)
  • Moxifloxacin (Avelox)
  • Nalidixic acid (NegGram)
  • Norfloxacin (Noroxin)
  • Sparfloxacin (Zagam)
  • Other antibiotics
  • Anticoagulants (‘blood thinners’) such as warfarin (Coumadin, Jantoven)
  • Certain antidepressants
  • Antipsychotics (medications to treat mental illness)
  • Cimetidine (Tagamet)
  • Cyclosporine (Gengraf, Neoral, Sandimmune)
  • Diuretics (‘water pills’)
  • Insulin and oral medications for diabetes such as glyburide (DiaBeta, Glynase, in Glucovance)
  • Certain medications for irregular heartbeat such as amiodarone (Cordarone, Nexterone, Pacerone), quinidine, procainamide, and sotalol (Betapace, Betapace AF, Sorine, Sotylize)
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others)
  • Probenecid (Probalan in Col-Probenecid)
  • Theophylline (Elixophyllin, Theo-24, Uniphyl, others)
  • Blood thinners (such as acenocoumarol, warfarin)
  • Strontium

Does food or alcohol interact with Zanocin® (ofloxacin)?

Zanocin® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Zanocin® (ofloxacin)?

Zanocin® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death)
  • An irregular or slow heartbeat or heart attack
  • A low level of potassium or magnesium in your blood
  • Diabetes
  • Liver disease
  • A kidney, heart, or lung transplant
  • Seizures
  • Epilepsy
  • Myasthenia gravis


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Zanocin® (ofloxacin).

What is the dose of Zanocin® (ofloxacin) for an adult?

The usual dose of Zanocin® tablets is 200 mg to 400 mg orally every 12 hours.

What is the dose of Zanocin® (ofloxacin) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Zanocin® (ofloxacin) available?

Zanocin® is available in the following dosage forms and strengths:

  • Tablets 200 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

Symptoms of overdose may include the following:

  • Drowsiness
  • Nausea
  • Dizziness
  • Hot and cold flushes
  • Numbness and swelling of the face
  • Slurred speech
  • Confusion

What should I do if I miss a dose?

If you miss a dose of Zanocin®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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