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Update Date 12/05/2020 . 4 mins read


What is Paderyl® (codeine phosphate hemihydrate) used for?

Paderyl® is commonly used for treatment mild to moderate cough suppressant.

How should I take Paderyl® (codeine phosphate hemihydrate)?

The dose of this medicine that is prescribed, how often to take it and how long to take it for depends on the condition being treated, your age and your kidney and liver function. It is important to follow the instructions given by your doctor. These will also be printed on the dispensing label that your pharmacist has put on the packet of medicine.

Codeine phosphate tablets can be taken either with or without food.

Do not exceed the prescribed dose of this medicine, or take it more frequently or for longer than prescribed by your doctor. Taking codeine regularly for a long time can lead to addiction, which might cause you to feel restless and irritable when you stop taking the tablets.

How do I store Paderyl® (codeine phosphate hemihydrate)?

Paderyl® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Paderyl® in the bathroom or the freezer. There may be different brands of Paderyl® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Paderyl® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Paderyl® (codeine phosphate hemihydrate)?

Before using this drug, tell your doctor if you are allergic to any ingredients of Paderyl®.

This drug is contraindicated in case of:

  • Respiratory depression
  • Obstructive airway disease
  • Asthma
  • Acute alcoholism
  • Convulsive disorders
  • Head injuries
  • Comatose patients
  • Raised intracranial pressure
  • Pregnancy (prolonged use or high doses at term)

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Paderyl® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Paderyl®.

Side effects

What side effects can occur from Paderyl® (codeine phosphate hemihydrate)?

When using this drug, some side effects may occur, including:

  • Dependence, withdrawal symptoms
  • Nausea
  • Vomiting
  • Constipation
  • Drowsiness
  • Confusion
  • Difficulty in micturition
  • Ureteric or biliary spasms
  • Urinary retention
  • Dry mouth
  • Dizziness
  • Sweating
  • Facial flushing
  • Headache
  • Vertigo
  • Bradycardia
  • Tachycardia
  • Palpitations
  • Orthostatic hypotension
  • Hypothermia
  • Restlessness
  • Mood changes
  • Decreased libido or potency
  • Hallucination
  • Miosis
  • Raised intracranial pressure
  • Muscle rigidity

In potentially fatal case, respiratory depression, hypotension, circulatory failure, deepening coma (larger doses), convulsions (especially in children and infants), rhabdomyolysis may occur.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Paderyl® (codeine phosphate hemihydrate)?

Paderyl® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Paderyl® (codeine phosphate hemihydrate)?

Paderyl® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Paderyl® (codeine phosphate hemihydrate)?

Paderyl® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Paderyl® (codeine phosphate hemihydrate).

What is the dose of Paderyl® (codeine phosphate hemihydrate) for an adult?

For analgesia: dosage should be adjusted according to the severity of the pain and the response of the patient.

The recommended dose is 15 to 60 mg every 4 to 6 hours (usual adult dose, 30 mg).

What is the dose of Paderyl® (codeine phosphate hemihydrate) for a child?

Children from 1 year of age and older: the recommended dose is 0.5 mg/kg of b.d. weight or 15 mg/m2 of b.d. surface every 4 to 6 hours.

Adolescents aged 12 to 18 years should not take this medicine more often than every six hours, or for longer than three days.

How is Paderyl® (codeine phosphate hemihydrate) available?

Paderyl® is available in the following dosage forms and strengths:

  • Syrup; Oral; Codeine Phosphate Hemihydrate 5 mg / 5 ml
  • Tablet, Film-Coated; Oral; Codeine Phosphate Hemihydrate 19.5 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Paderyl®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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