By Medically reviewed by Hello Doktor Medical Panel


What is Trymo (Colloidal bismuth subcitrate) used for?

Trymo is commonly used for duodenal ulcers, chronic active gastritis, benign gastric ulcer, non-ulcer dyspepsia.

Colloidal bismuth subcitrate can be used as triple therapy (with metronidazole and either tetracycline or amoxicillin) to eradicate Helicobacter pylori.

How should I take Trymo (Colloidal bismuth subcitrate)?

Take Trymo with an empty stomach, half an hour before meals to be swallowed whole and not chewed.

Please consult with your doctor or pharmacist for more information.

How do I store Trymo (Colloidal bismuth subcitrate)?

Trymo is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Trymo in the bathroom or the freezer. There may be different brands of Trymo that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Trymo down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Trymo (Colloidal bismuth subcitrate)?

Before using this drug, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using this medication during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication.

Side effects

What side effects can occur from Trymo (Colloidal bismuth subcitrate)?

Some side effects can happen when using Trymo, these are:

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Giddiness
  • Darkening of the stools

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Trymo (Colloidal bismuth subcitrate)?

Trymo may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products  may interact with Trymo including:

  • The absorption of iron, calcium or tetracycline may be reduced after their concomitant administration with Trymo.
  • Antacids or milk given along with Trymo may form a chelate and interfere with the action of colloidal bismuth subcitrate. Thus, it is advised that food or antacids should not be taken within 30 minutes before or after administration of Trymo.

Does food or alcohol interact with Trymo (Colloidal bismuth subcitrate)?

Trymo may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Trymo (Colloidal bismuth subcitrate)?

Trymo may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Trymo (Colloidal bismuth subcitrate)?

What is the dose of Trymo (Colloidal bismuth subcitrate) for an adult?

The recommended dose is two tablets twice a day.

Trymo should be initially used for a period of 4 weeks and if required up to a maximum of 8 weeks. It should not be used as maintenance therapy after 8 weeks. Before the therapy is restarted, it is advised to give a gap at least 8 weeks.

When used as a part of triple therapy, 1 tablet of Trymo is given 4 times daily for 2 weeks.

What is the dose of Trymo (Colloidal bismuth subcitrate) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Trymo (Colloidal bismuth subcitrate) available?

Trymo is available in the following dosage forms and strengths:

  • Tablets, Film-Coated; Tripotassium Dicitratobismuthate 120 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Trymo, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: December 22, 2016 | Last Modified: December 19, 2019

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