Update Date 11/05/2020 . 5 mins read
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What is Naphcon-A® (naphazoline and pheniramine) used for?

Naphcon-A® is commonly used to treat eye irritation due to allergies.

How should I take Naphcon-A® (naphazoline and pheniramine)?

Use this medicine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • For the eye only.
  • Wash your hands before use.
  • Take out contact lenses before using Naphcon-A®. Talk with your doctor to see when lenses may be put back in after this medicine is given. Do not put contacts back in if your eyes are irritated or infected.
  • Do not touch the container tip to the eye, lid, or other skin.
  • Tilt your head back and drop drug into the eye.
  • After use, keep your eyes closed. Put pressure on the inside corner of the eye. Do this for 1 to 2 minutes. This keeps the drug in your eye.
  • Put the cap back on after you are done using your dose.
  • Do not use if solution changes color.
  • Do not use if the solution is cloudy, leaking, or has particles.

How do I store Naphcon-A® (naphazoline and pheniramine)?

Naphcon-A® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Naphcon-A® in the bathroom or the freezer. There may be different brands of Naphcon-A® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Naphcon-A® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Naphcon-A® (naphazoline and pheniramine)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Naphcon-A® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

For all patients taking Naphcon-A®:

  • Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists.
  • Use care when driving or doing other tasks that call for clear eyesight.
  • Bright lights may bother you. Wear sunglasses.
  • Do not use for longer than you were told by the doctor or on the product label. Using too much or for too long may cause more eye redness.
  • This medicine may cause harm if swallowed. If Naphcon-A® is swallowed, call a doctor or poison control center right away.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.


  • Talk with the doctor before you give Naphcon-A to a child younger than 6 years old.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Naphcon-A® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Naphcon-A®. Naphcon-A® is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Naphcon-A® (naphazoline and pheniramine)?

Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Change in eyesight, eye pain, or very bad eye irritation.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Naphcon-A® (naphazoline and pheniramine)?

Naphcon-A® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Naphcon-A® (naphazoline and pheniramine)?

Naphcon-A® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Naphcon-A® (naphazoline and pheniramine)?

Naphcon-A® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Naphcon-A® (naphazoline and pheniramine).

What is the dose of Naphcon-A® (naphazoline and pheniramine) for an adult?

Consult your doctor for further information.

What is the dose of Naphcon-A® (naphazoline and pheniramine) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Naphcon-A® (naphazoline and pheniramine) available?

Naphcon-A® is available in the following dosage forms and strengths:

  • Eye drops

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Naphcon-A®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

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