By Medically reviewed by Hello Doktor Medical Panel

Know the basics

What is Komix® (Dextromethorphan HBr Syrup) used for?

Komix® is a cough suppressant, commonly used for treating cough. It will not treat a cough caused by smoking, asthma, or emphysema.

How should I take Komix® (Dextromethorphan HBr Syrup)?

For orally taken form, you should:

  • Take Komix® by mouth as directed by your doctor concerning: dose, schedule.
  • Read the label carefully before using Komix®.
  • Consult your doctor for any information on the label that you do not clearly understand.

How do I store Komix® (Dextromethorphan HBr Syrup)?

Komix® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Komix® in the bathroom or the freezer. There may be different brands of Komix® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Komix® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Know the precautions & warnings

What should I know before using Komix® (Dextromethorphan HBr Syrup)?

Before using Komix®, tell your doctor if you have:

  • Allergic reaction: to Komix®, excipients using for dosage form containing Komix®. The information is detailed in the leaflet.
  • Allergic reaction to any other medicines, foods, dyes, preservatives, or animals.
  • Pediatric.
  • Geriatric.
  • Used any other health conditions, drugs that have a risk of interaction with Komix®.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Komix® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Komix®. Komix® is pregnancy risk category C,  according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk;
  • B=No risk in some studies;
  • C=There may be some risk;
  • D=Positive evidence of risk;
  • X=Contraindicated;
  • N=Unknown.

Know the side effects

What side effects can occur from Komix®?

As taking others medicines, taking Komix® can cause some side effects. Most of them are rarely occurring and do not need any supplementary treatment. However, it is always important for you to consult your doctor if you have any problem after taking this medicine.

Some of the side effects are listed below:

  • Severe dizziness, anxiety, restless feeling, or nervousness;
  • Confusion, hallucinations;
  • Slow, shallow breathing;
  • Stomach upset.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Know the interactions

What drugs may interact with Komix® (Dextromethorphan HBr Syrup)?

Komix® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval, such as:

Almotriptan; Amitriptyline; Amoxapine;


Citalopram; Clomipramine; Darunavir;

Desipramine; Desvenlafaxine; Dolasetron;






Granisetron; Hydroxytryptophan; Imipramine;


Levomilnacipran; Linezolid;





Mirtazapine; Nortriptyline; Palonosetron; Panobinostat;






Trazodone; Trimipramine; Venlafaxine;








Iproniazid; Isocarboxazid;

Fluvoxamine; Moclobemide;







Toloxatone; Tranylcypromine.

Does food or alcohol interact with Komix® (Dextromethorphan HBr Syrup)?

Komix® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Komix® (Dextromethorphan HBr Syrup)?

Komix® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, such as:

  • Asthma;
  • Diabetes (sugar diabetes);
  • Liver disease;
  • Chronic bronchitis;
  • Emphysema;
  • Mucus or phlegm with cough;
  • Slowed breathing.

Understand the dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Komix® (Dextromethorphan HBr Syrup).

What is the dose of Komix® (Dextromethorphan HBr Syrup) for an adult?

Consult your doctor for information about the dose of Komix® hydrochloride is 10 to 30 mg orally every 4 to 8 hours.

What is the dose of Komix® (Dextromethorphan HBr Syrup) for a child?

Consult your doctor for information about the dose of Komix® hydrochloride. Recommended doses in some cases are listed below:

  • For children from 1 to 3 months:0.5 to 1 mg orally every 6 to 8 hours.
  • For children from 4 to 6 months: 1 to 2 mg orally every 6 to 8 hours
  • For children from 7 months to 1 year: 2 to 4 mg orally every 6 to 8 hours.
  • For children from 2 to 6 years: 5 mg/5 mL oral liquid: 5 mL orally every 4 hours. Maximum dose is 30 mg/day.
  • For children from 7 to 12 years: 5 mg/5 mL oral liquid: 10 mL orally every 4 hours. Maximum dose is 60 mg/day.
  • For children from 12 years or older: 10 to 30 mg orally every 4 to 8 hours.
    Maximum dose: 120 mg/day.

How is Komix® (Dextromethorphan HBr Syrup) available?

Komix® is available in the following dosage forms and strengths: 7.5 mg/0.8 ml; 7.5 mg/5 ml; 10 mg/5 ml; 15 mg/5 ml; 15 mg ; 5 mg ; 7.5 mg ; 12.5 mg/5 ml; 30 mg/5 ml; 2.5 mg.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services (115) or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Komix®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: October 9, 2016 | Last Modified: December 19, 2019

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