Aprovel

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Kemas kini Tarikh 12/05/2020 . 4 minit bacaan
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Uses

What is Aprovel used for?

Aprovel is commonly used for treating hypertension, renal disease in hypertensive type II diabetic patients.

Aprovel may be prescribed for other uses. Ask your doctor or pharmacist for more information.

How should I take Aprovel?

Do not crush, break, or chew the tablets. Swallow Aprovel whole with a glass of water.

Ask your health care provider any questions you may have about how to use medication.

How do I store Aprovel?

Aprovel is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Aprovel in the bathroom or the freezer. There may be different brands of Aprovel that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Aprovel down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product

Precautions & warnings

What should I know before using medication?

Consult with your doctor or pharmacist, if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Aprovel or other medications.
  • You have any other types of allergies, such as to foods, dyes, preservatives, or animals.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using this medication during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication. This medication pregnancy risk category 1st trimester – C; 2nd and 3rd trimesters – D, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk;
  • B=No risk in some studies;
  • C=There may be some risk;
  • D=Positive evidence of risk;
  • X=Contraindicated;
  • N=Unknown.

Breastfeeding:

Potential harm to nursing infant; discontinue drug, or do not nurse.

Always consult your health care provider prior to using this medication if you are pregnant, breastfeeding.

Side effects

What side effects can occur from Aprovel?

Here are side effects may occur:

  • Dizziness;
  • Nausea;
  • Fatigue;
  • Increased plasma creatine kinase;
  • Orthostatic hypotension;
  • Musculoskeletal pain;
  • Hyperkalaemia in type II diabetes with renal disease.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Aprovel?

Aprovel may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Aprovel may cause interactions with these medications, such as:

  • K+-sparing diuretics;
  • K+supplements;
  • Other antihypertensives;
  • Lithium;
  • NSAIDs;
  • Aspirin.

Does food or alcohol interact with Aprovel?

Aprovel may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Aprovel?

Aprovel may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, such as:

  • A history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness), including angioedema caused by treatment with an angiotensin-converting enzyme (ACE) inhibitor (e.g., lisinopril).
  • A history of heart problems (e.g., heart failure).
  • Blood vessel problems.
  • Blood flow problems.
  • Diabetes.
  • Kidney problems.
  • A history of stroke or recent heart attack.
  • Being dehydrated.
  • Have low blood volume.
  • Electrolyte problems (e.g., high blood potassium levels, low blood sodium levels).
  • Are on a low-salt (sodium) diet.
  • Being dialysis.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.

What is the dose of Aprovel for an adult?

  • Initially 150mg once daily. Increase if necessary to 300mg once daily or add other antihypertensives.
  • Renal disease, initially 150mg once daily, titrate to 300mg once daily for maintenance.

What is the dose of Aprovel for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Aprovel available?

Aprovel is available in the following dosage forms and strengths

  • Aprovel film-coated tab 150 mg.
  • Aprovel film-coated tab 300 mg.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services (115) or go to your nearest emergency room.

It is also important to carry a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking with you in case of emergencies.

What should I do if I miss a dose?

If you miss a dose of medication, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

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