The Effects of Anaphylaxis on the Body

By Medically reviewed by hellodoktor

Anaphylaxis is the most serious complications allergies. This deadly reaction not only occurs in children but also in adults. If undiagnosed and treated promptly, it confuses not only the patients but also for doctors treating. The disease appears briefly, immediately or after a 30-minute dosing, a bee sting or after eating strange foods

Anaphylaxis is a type of failure circulatory respiratory due to the release of vasoactive mediators (histamine) that are activated by the immune response. It occurs after putting on the body an allergen on an available body sensitivity to the substance. The consequence of this situation is the increasing of vascular permeability, vasodilation, smooth muscle contraction. Symptoms can start very early in seconds, minutes or hours after exposure to allergy-causing agents, and can progress rapidly. Clinical symptoms of drug-induced anaphylaxis or other causes are basically the same and occur in all organs in the body.

Immune system

Your immune system is to fight against antigens such as bacteria, viruses, and fungi. It will identify harmful substances and neutralize their effects. Once the immune system is exposed to an antigen substance, it stores the information for future use. Sometimes, you come into contact with the antigen again, your immune system will react strongly and beyond control. Too much histamine and other inflammatory chemicals exploding in your body will cause serious problem.

Respiratory system

Inflammation in the respiratory system can cause bronchial tissues swell. Therefore, the patient had difficulty in breathing, choking, cyanosis, respiratory distress due to bronchospasm choking. Also, anaphylaxis causes vocal cord edema, edema intubation, bronchospasm, pulmonary edema. Respiratory failure is a case of life-threatening emergency requiring immediate treatment. If untreated, it can lead to cease respiration.

Cardiovascular system

The reactions such as varicose veins, hypotension, cardiovascular collapse usually occur as a result of the chemicals introduced into the body. Moreover, lack of oxygen in the blood, reducing the volume of circulating blood leads to melting. And decreased myocardial contractility is an higher stage of anaphylaxis.

Nervous system

Patients quickly get headaches, dizziness, limb tremors, convulsions and possibly systemic fainting, or unconsciousness. Anaphylaxis can cause perceptual disturbances, anxiety, and depression. Other symptoms include stuttering, hoarseness, and difficult speaking.

Digestive system

If anaphylaxis caused by food or medicines orally reasons, patients will get severe effects. They are abdominal pain, nausea, vomiting, uncontrolled diarrhea, cramps, and even gastrointestinal bleeding.


Signs of anaphylaxis can be seen on the skin. The skin will get itching, rash, urticaria, Quincke edema. Swells will appear suddenly and rapidly on both the bottom and the surface of the skin and mucosa. It mainly appears on the tongue, lips, eyes, mouth, hands, feet, throat, and genitals. If the respiratory system of a person with anaphylaxis is in trouble, the skin may become pale because of the lack of oxygen.

The severity of anaphylaxis depends on the sensitivity of each body. The number and speed of absorption of unwanted substance into the body and depends on the processing time of treatment. The early signs to note are itchy hands and legs, numb lips, tongue, difficulty breathing, rapid heart beat, feeling restless, and jittery.


Hello Health Group does not provide medical advice, diagnosis or treatment.

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