The Effects of Anaphylaxis on the Body

Medically reviewed by | By

Update Date May 12, 2020
Share now

Anaphylaxis is the most serious complications allergies. This deadly reaction not only occurs in children but also in adults. If undiagnosed and treated promptly, it confuses not only the patients but also for doctors treating. The disease appears briefly, immediately or after a 30-minute dosing, a bee sting or after eating strange foods

Anaphylaxis is a type of failure circulatory respiratory due to the release of vasoactive mediators (histamine) that are activated by the immune response. It occurs after putting on the body an allergen on an available body sensitivity to the substance. The consequence of this situation is the increasing of vascular permeability, vasodilation, smooth muscle contraction. Symptoms can start very early in seconds, minutes or hours after exposure to allergy-causing agents, and can progress rapidly. Clinical symptoms of drug-induced anaphylaxis or other causes are basically the same and occur in all organs in the body.

Immune system

Your immune system is to fight against antigens such as bacteria, viruses, and fungi. It will identify harmful substances and neutralize their effects. Once the immune system is exposed to an antigen substance, it stores the information for future use. Sometimes, you come into contact with the antigen again, your immune system will react strongly and beyond control. Too much histamine and other inflammatory chemicals exploding in your body will cause serious problem.

Respiratory system

Inflammation in the respiratory system can cause bronchial tissues swell. Therefore, the patient had difficulty in breathing, choking, cyanosis, respiratory distress due to bronchospasm choking. Also, anaphylaxis causes vocal cord edema, edema intubation, bronchospasm, pulmonary edema. Respiratory failure is a case of life-threatening emergency requiring immediate treatment. If untreated, it can lead to cease respiration.

Cardiovascular system

The reactions such as varicose veins, hypotension, cardiovascular collapse usually occur as a result of the chemicals introduced into the body. Moreover, lack of oxygen in the blood, reducing the volume of circulating blood leads to melting. And decreased myocardial contractility is an higher stage of anaphylaxis.

Nervous system

Patients quickly get headaches, dizziness, limb tremors, convulsions and possibly systemic fainting, or unconsciousness. Anaphylaxis can cause perceptual disturbances, anxiety, and depression. Other symptoms include stuttering, hoarseness, and difficult speaking.

Digestive system

If anaphylaxis caused by food or medicines orally reasons, patients will get severe effects. They are abdominal pain, nausea, vomiting, uncontrolled diarrhea, cramps, and even gastrointestinal bleeding.


Signs of anaphylaxis can be seen on the skin. The skin will get itching, rash, urticaria, Quincke edema. Swells will appear suddenly and rapidly on both the bottom and the surface of the skin and mucosa. It mainly appears on the tongue, lips, eyes, mouth, hands, feet, throat, and genitals. If the respiratory system of a person with anaphylaxis is in trouble, the skin may become pale because of the lack of oxygen.

The severity of anaphylaxis depends on the sensitivity of each body. The number and speed of absorption of unwanted substance into the body and depends on the processing time of treatment. The early signs to note are itchy hands and legs, numb lips, tongue, difficulty breathing, rapid heart beat, feeling restless, and jittery.


Hello Health Group does not provide medical advice, diagnosis or treatment.

Read also:

    Was this article helpful for you ?
    happy unhappy"

    You might also like

    Trivial Skin Diseases that Could Worsen without Care

    While not all skin conditions need urgent treatment, one should never take their supposed trivial skin diseases lightly as they can worsen over time. 

    Medically reviewed by Hello Doktor Medical Panel
    Written by Ahmad Wazir Aiman Mohd Abdul Wahab
    Skin Care, Beauty December 20, 2019

    Update On Current Management of Psoriasis

    Psoriasis is chronic condition that poses physical and emotional stress on the patient. Current management of Psoriasis is discussed in this article.

    Medically reviewed by Panel Perubatan Hello Doktor
    Written by Ahmad Wazir Aiman Mohd Abdul Wahab

    Why Do So Many Skin Care Products Have Urea for Dry Skin?

    Primarily produced from the metabolism of dietary protein and other organic nitrogen compounds in the liver, urea or carbamide is excreted in the urine and sweat as a waste product. Urea is also commonly used in ...

    Medically reviewed by Panel Perubatan Hello Doktor
    Written by Helma Hassan
    Healthy Living, Beauty March 6, 2019

    Love Swimming? Know The Tips to Protect Your Skin from Chlorine

    Swimming is generally considered to be a healthy sports activity for both children and adults. However, if you are an avid swimmer, you probably notice that indoor swimming cause more than just wrinkle fingers ...

    Medically reviewed by Panel Perubatan Hello Doktor
    Written by Helma Hassan

    Recommended for you

    arthritis psoriasis

    Every 1 in 3 Psoriasis Patients Develops Arthritis

    Medically reviewed by Dr. Joseph Tan
    Written by Aaron Joseph Sta Maria
    Published on April 9, 2020

    Why You Should Not Be Worried About Biologic Treatment for Psoriasis

    Medically reviewed by Dr. Joseph Tan
    Written by Aaron Joseph Sta Maria
    Published on April 8, 2020

    Chronic Diseases that Stem from Untreated Psoriasis

    Medically reviewed by Dr. Joseph Tan
    Written by Aaron Joseph Sta Maria
    Published on April 8, 2020
    kulit merekah

    This is How Skin Cracks

    Written by Aaron Joseph Sta Maria
    Published on December 20, 2019