What is mesoglycan used for?

Mesoglycan is a substance obtained from cow lung or cow blood vessel (aorta) or pig intestine. It is used as medicine for various blood vessel disorders. Depending on the use, mesoglycan is taken by mouth, or applied to the skin, or given by injection into the muscle (intramuscularly) or the bloodstream (intravenously, by IV).

Mesoglycan is used for treating:

  • Atherosclerosis
  • Hemorrhoids
  • Vasculitis
  • Poor blood circulation that can lead to varicose veins and other blood vessel problems
  • Leg ulcers
  • High blood fat levels, especially high triglycerides
  • Stroke

It is also used for reducing leg pain during walking that is often experienced by people with peripheral artery disease (PAD).

Mesoglycan is sometimes used to improve thinking skills in people with poor blood circulation in the brain.

Another use is prevention of blood clots in the legs (deep venous thrombosis, DVT).

Mesoglycan is sometimes applied directly to the skin for treating leg ulcers.

Healthcare providers give mesoglycan as a shot to treat poor blood circulation, leg ulcers, heart disease, and stroke. They give it intravenously to treat lower limb ischemia, a condition in which enough oxygen doesn’t get to the tissues in the legs because of blood vessel problems.

How does it work?

There are not enough studies about how mesoglycan works. Please discuss with your doctor for more information. However, it is known that mesoglycan has effects that improve blood flow and reduce the risk of clotting.

Precautions & warnings

What should I know before using mesoglycan?

Consult with your doctor or pharmacist or herbalist, if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription.
  • You have allergy with any substances of mesoglycan or other medications or other herbs.
  • You have any other illnesses, disorders, or medical conditions.
  • You have any other types of allergies, such as to foods, dyes, preservatives, or animals.

The regulations for a supplement are less strict than the regulations for a drug. More studies are needed to determine its safety. The benefits of taking this supplement must outweigh the risks before use. Consult with your doctor for more information.

How safe is mesoglycan?

Mesoglycan is possibly safe for most adults when taken by mouth.

Because mesoglycan comes from animal products, there is a risk that diseases could be accidentally transmitted from sick animals.

There isn’t enough information to know whether mesoglycan is safe when used applied to the skin or given intravenously (by IV).

Special precautions & warnings

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking mesoglycan if you are pregnant or breast-feeding. Stay on the safe side and avoid use.

Bleeding disorders: Mesoglycan might cause bleeding in people with clotting problems. Use with caution.

An allergy to the blood thinner heparin: Mesoglycan might cause allergic reactions in people who are allergic to heparin or related drugs.

Surgery: Mesoglycan might slow blood clotting. There is some concern that it might cause extra bleeding if used near the time of surgery. Stop using mesoglycan at least 2 weeks before a scheduled surgery.

Side effects

What kind of side effects may I have from mesoglycan?

Mesoglycan can cause nausea, vomiting, heartburn, headache, diarrhea, and skin reactions. Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about side effects, please consult your doctor.


What interactions may I have with mesoglycan?

Mesoglycan may interact with your current medications or medical conditions. Consult with your doctor before using.

Products that may interact with mesoglycan include:

  • Thrombolytic drugs

Mesoglycan decreases blood clotting. Taking mesoglycan with medications used for dissolving blood clots might increase the chance of bleeding and bruising.

Some medications used for dissolving blood clots include alteplase (Activase), anistreplase (Eminase), reteplase (Retevase), streptokinase (Streptase), and urokinase (Abbokinase).

  • Anticoagulant / Antiplatelet drugs

Mesoglycan might slow blood clotting. Taking mesoglycan along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.


The information provided is not a substitute for medical advice. ALWAYS consult your doctor before using this medication.

What is the usual dose for mesoglycan?

The following doses have been studied in scientific research:


  • For preventing disorders of blood flow to the brain: mesoglycan 100-144 mg per day.
  • For high triglycerides: mesoglycan 96 mg per day.
  • For poor blood circulation: 50 mg three times daily.


  • Healthcare providers give mesoglycan shots to treat cerebrovascular disease, poor blood circulation, and ulcers caused by poor circulation.

The dose for mesoglycan may be different for every patient. The dose that you take depends on your age, health, and several other conditions. Supplements are not always safe. Please discuss with your doctor for your appropriate dosage.

What form does mesoglycan come in?

Mesoglycan may be available in the following forms:

  • Encapsulated mesoglycan

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: September 18, 2017 | Last Modified: September 21, 2017

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