By Medically reviewed by Hello Doktor Medical Panel


What is Zenpro® (omeprazole) used for?

Zenpro® belongs to group of drugs called proton pump inhibitors. It decreases the amount of acid produced in the stomach.

Zenpro® is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions caused by excess stomach acid. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

Zenpro® may also be given together with antibiotics to treat gastric ulcer caused by infection with helicobacter pylori (H. pylori).

How should I take Zenpro® (omeprazole)?

Zenpro® is usually taken before eating (at least 1 hour before a meal). Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Zenpro® should be taken only once every 24 hours for 14 days. Take the medicine in the morning before you eat breakfast. It may take up to 4 days for full effect. Do not take more than one tablet every 24 hours.

Allow at least 4 months to pass before you start another 14-day treatment with Zenpro®. Call your doctor if you have additional symptoms and need treatment before the 4 months has passed.

How do I store Zenpro® (omeprazole)?

Zenpro® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Zenpro® in the bathroom or the freezer. There may be different brands of Zenpro® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Zenpro® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Zenpro® (omeprazole)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Zenpro® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.

Ask a doctor or pharmacist if it is safe for you to use Zenpro® if you have other medical conditions, especially:

  • Liver disease
  • Low levels of magnesium in your blood
  • Osteoporosis or low bone mineral density (osteopenia)

Do not use Zenpro® without the advice of a doctor if you have:

  • Trouble or pain with swallowing
  • Bloody or black stools, vomit that looks like blood or coffee grounds
  • Heartburn that has lasted for over 3 months
  • Frequent chest pain, heartburn with wheezing
  • Unexplained weight loss
  • Nausea or vomiting, stomach pain

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Zenpro® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Zenpro®.

Side effects

What side effects can occur from Zenpro® (omeprazole)?

Common side effects may include:

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Zenpro® (omeprazole)?

Zenpro® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • Cilostazol
  • Clopidogrel
  • Diazepam (Valium)
  • Digoxin
  • Disulfiram (Antabuse)
  • Erlotinib
  • Iron-containing medicines (ferrous fumarate, ferrous gluconate, ferrous sulfate, and others)
  • Methotrexate
  • Mycophenolate mofetil
  • Phenytoin
  • John’s wort
  • Tacrolimus
  • Warfarin (Coumadin, Jantoven)
  • An antibiotic–ampicillin, amoxicillin, clarithromycin, rifampin
  • Antifungal medicine–ketoconazole, voriconazole
  • HIV or AIDS medication–atazanavir, nelfinavir, saquinavir

Does food or alcohol interact with Zenpro® (omeprazole)?

Zenpro® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Zenpro® (omeprazole)?

Zenpro® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Zenpro® (omeprazole).

What is the dose of Zenpro® (omeprazole) for an adult?

Usual Adult Dose for Duodenal Ulcer:

20 mg orally once a day before a meal. Most patients heal within 4 to 8 weeks.

Usual Adult Dose for Helicobacter pylori Infection:

Dual therapy: Zenpro® 40 mg orally once a day in the morning plus clarithromycin 500 mg orally 3 times a day on days 1 to 14. Beginning on day 15, Zenpro® 20 mg orally once a day in the morning on days 15 to 28.

Triple therapy: Zenpro® 20 mg plus clarithromycin 500 mg plus amoxicillin 1000 mg all given orally twice a day for 10 days. If an ulcer is present at the initiation of therapy, continue Zenpro® 20 mg orally once a day for an additional 18 days.

Usual Adult Dose for Gastric Ulcer:

40 mg orally once a day before a meal for 4 to 8 weeks.

Usual Adult Dose for Zollinger-Ellison Syndrome:

Initial: 60 mg orally once a day. Dosage should be individualized to patient’s needs.

Maintenance: doses up to 120 mg 3 times a day have been administered. Daily doses greater than 80 mg should be divided.

What is the dose of Zenpro® (omeprazole) for a child?

Usual Pediatric Dose for Erosive Esophagitis:

Infants: GERD: 0.7 mg/kg/dose once daily

Children and Adolescents 1 to 16 years: GERD, ulcers, esophagitis:

  • 5 kg to less than 10 kg: 5 mg once daily
  • 10 kg to less than or equal to 20 kg: 10 mg once daily
  • Greater than 20 kg: 20 mg once daily

Usual Pediatric Dose for Gastroesophageal Reflux Disease:

Infants: GERD: 0.7 mg/kg/dose once daily.

Children and Adolescents 1 to 16 years: GERD, ulcers, esophagitis:

  • 5 kg to less than 10 kg: 5 mg once daily
  • 10 kg to less than or equal to 20 kg: 10 mg once daily
  • Greater than 20 kg: 20 mg once daily

How is Zenpro® (omeprazole) available?

Zenpro® is available in the following dosage forms and strengths:

  • Capsule 20mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Zenpro®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

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Review Date: August 24, 2017 | Last Modified: December 19, 2019

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