By Medically reviewed by Panel Perubatan Hello Doktor


What is Tazocin® (piperacillin/ tazobactam) used for?

Tazocin® is commonly used for treating moderate to severe infections caused by certain bacteria.

How should I take Tazocin® (piperacillin/ tazobactam)?

Use Tazocin® as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Tazocin® is usually given as an injection at your doctor’s office, hospital, or clinic. If you will be using Tazocin® at home, a health care provider will teach you how to use it. Be sure you understand how to use Tazocin®. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

Do not use piperacillin/tazobactam if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

How do I store Tazocin® (piperacillin/ tazobactam)?

Tazocin® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Tazocin® in the bathroom or the freezer. There may be different brands of Tazocin® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Tazocin® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Tazocin® (piperacillin/ tazobactam)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Tazocin® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Tazocin® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Tazocin®. Tazocin® is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Tazocin® (piperacillin/ tazobactam)?

Some side effects may occur when using this drug, such as:

Seek medical attention right away if severe allergic reactions occur.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Tazocin® (piperacillin/ tazobactam)?

Tazocin® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug, such as:

  • Chemotherapy or diuretics (e.g., furosemide, hydrochlorothiazide)
  • Probenecid
  • Anticoagulants (e.g., warfarin)
  • Heparin
  • Methotrexate
  • Ondepolarizing muscle relaxants (e.g., vecuronium)
  • Aminoglycosides (e.g., tobramycin)
  • Oral contraceptives (birth control pills)

Does food or alcohol interact with Tazocin® (piperacillin/ tazobactam)?

Tazocin® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Tazocin® (piperacillin/ tazobactam)?

Tazocin® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Cystic fibrosis
  • Bowel inflammation
  • Bleeding problems
  • Congestive heart failure
  • Kidney problems
  • Dialysis
  • A history of severe diarrhea or bowel problems due to an antibiotic
  • A salt-restricted diet
  • Low blood potassium levels


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Tazocin® (piperacillin/ tazobactam).

What is the dose of Tazocin® (piperacillin/ tazobactam) for an adult?

Intra-abdominal Infection

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used.


3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used.

Skin or Soft Tissue Infection

3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used.


3.375 g IV every 6 hours; 4.5 g IV every 8 hours has also been used.

What is the dose of Tazocin® (piperacillin/ tazobactam) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Tazocin® (piperacillin/ tazobactam) available?

Tazocin® is available in the following dosage forms and strengths:

  • Intravenous powder for injection, intravenous solution

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Tazocin®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

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Review Date: June 16, 2017 | Last Modified: December 19, 2019

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