What is Tanatril® (Imidapril Hydrochloride) used for?
Tanatril® is one of the groups of ACE (angiotensin-converting enzyme) inhibitors. It is commonly used for treating high blood pressure (hypertension).
Tanatril® works by widening blood vessels, so that blood passes through them more easily. Since blood pressure depends on the diameter of blood vessels, your blood pressure will be lowered by Tanatril®. Also, it will be easier for your heart to pump blood through the vessels around the body.
How should I take Tanatril® (Imidapril Hydrochloride)?
To take Tanatril®,
- Take Tanatril® once daily, exactly as your doctor tells you to. Your doctor may advise you to take your very first dose at bedtime. This is because you may feel dizzy when you first start taking it.
- With the exception of the first dose, you can generally take imidapril at a time of day that suits you. However, you should try to take each of your doses at the same time of day, each day.
- Swallow the tablet with a drink of water. You should take imidapril about 15 minutes before a meal.
- There are several strengths of imidapril tablets. It is usual to start by taking the 5 mg strength tablet. You may be asked to take only half of a tablet to begin with, although it is more usual to take a whole tablet. Your doctor may gradually increase your dose over the following few weeks. This allows your doctor to make sure that you have the dose that helps your condition but helps to avoid any unwanted side-effects, such as dizziness. Each time you collect a new supply, check to make sure the tablets are the strength that you are expecting.
How do I store Tanatril® (Imidapril Hydrochloride)?
Tanatril® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Tanatril® in the bathroom or the freezer. There may be different brands of Tanatril® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush Tanatril® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Precautions & warnings
What should I know before using Tanatril® (Imidapril Hydrochloride)?
Do not take Tanatril® if you are allergic to imidapril, other ACE inhibitors or any of the other ingredients of this medicine.
Is it safe during pregnancy or breastfeeding?
You must tell your doctor if you think you are (or might become) pregnant. Your doctor will normally advise you to stop taking Tanatril® before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Tanatril®.
Tanatril® is not recommended in early pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
Tell your doctor if you are breastfeeding or start breastfeeding. Tanatril® is not recommended for mothers who are breastfeeding, and your doctor may choose another treatment for you if you wish to breastfeed, especially if your baby is new-born, or was born prematurely.
What side effects can occur from Tanatril® (Imidapril Hydrochloride)?
Tell your doctor or pharmacist, if you develop any of the following side effects.
Rare side effects which may act up to 1 in 1000 people:
- Reduction (lowering of number) of white blood cells, which makes infections more likely.
- Reduction (lowering of number) of red blood cells, which can make the skin pale and cause weakness and breathlessness.
Uncommon side effects which may act up to 1 in 100 people:
- Feeling your heartbeat (palpitations)
- Narrowing of the blood vessels in the brain (cerebrovascular disease)
- Tingling or numbness in the hands or feet
- Swelling and irritation inside the nose
- Pain in the upper abdomen
- Indigestion (stomach upset)
- Viral infection
- Upper respiratory tract infection
- Chest pain
- Pain in limbs
- Swelling of the fingers, legs and toes(oedema)
Common side effects which may act up to 1 in 10 people:
- Feeling sick (nausea).
It is very important that you immediately contact your doctor and stop taking Tanatril® if you develop any of the following symptoms:
- Headache; dizziness; light headedness, perhaps along with impaired vision
- Difficulty in breathing
- Rash or itching
- A serious allergic reaction (swelling of your face or throat – angioedema)
- Blistering of the skin, mouth, eyes and genitals (toxic epidermal necrolysis, Stevens-Johnson syndrome)
- Yellowing of the skin or whites of the eyes caused by liver or blood problems (jaundice)
Tanatril® may also cause changes in the composition of your blood. Your doctor will conduct regular blood tests and will explain the results to you.
What drugs may interact with Tanatril® (Imidapril Hydrochloride)?
Tanatril® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Does food or alcohol interact with Tanatril® (Imidapril Hydrochloride)?
Tanatril® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
What health conditions may interact with Tanatril® (Imidapril Hydrochloride)?
Consult with your doctor:
- If you have any problems with your kidneys or liver.
- If you are dehydrated – for example, if you have had diarrhea or sickness very recently.
- If you have been told you have atherosclerosis (a build-up of fatty deposits on the walls of your arteries).
- If you have peripheral vascular disease (a particular type of poor circulation).
- If you have collagen vascular diseases such as systemic lupus erythematosus (SLE) or scleroderma.
- If you have been told you have cardiomyopathy (heart muscle disease), or aortic stenosis (narrowing of the main blood vessel from your heart).
- If you have ever had angioedema (where your face, tongue or throat swells).
- If you are having desensitization treatment to protect against bee and wasp stings.
- If you have dialysis treatment, or treatment to remove cholesterol from your blood by a machine (LDL apheresis).
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Tanatril® (Imidapril Hydrochloride).
What is the dose of Tanatril® (Imidapril Hydrochloride) for an adult?
The usual starting dose is 5 mg per day. After 3 weeks your blood pressure needs to be measured again to check the results. Your doctor might increase the daily dose to 10 mg or even 20 mg.
The doctor may want you to start on 2.5 mg once a day, if:
- You have mild kidney problems or liver problems.
- You have heart problems, chest pain, problems related to blood vessels in the brain, low salt and/or fluid levels.
- There is a risk that your blood pressure could fall suddenly.
Patients over 65 years of age, your doctor will start the treatment with 2.5 mg once a day and increase this to 10 mg depending on how you get on.
What is the dose of Tanatril® (Imidapril Hydrochloride) for a child?
The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.
How is Tanatril® (Imidapril Hydrochloride) available?
Tanatril® is available in the following dosage forms and strengths:
- Tablet 5mg
- Tablet 10mg
- Tablet 20mg
What should I do in case of an emergency or overdose?
If you have accidentally taken more than your prescribed dose, contact your doctor immediately. Remember to take the pack and any remaining tablets with you.
The most common signs and symptoms of overdose are fall in blood pressure, shock, and stupor (a state of almost complete lack of consciousness), slower heartbeat, disturbances in the levels of potassium or other electrolytes and kidney failure. This can result in a feeling of general discomfort, feeling your heartbeat or in swelling of the fingers, legs and toes (edema).
What should I do if I miss a dose?
Simply leave out that dose completely and then take your next dose at the right time. Do not take a double dose to make up for a forgotten dose.
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