Tamiflu

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Kemas kini Tarikh 12/05/2020 . 7 minit bacaan
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Uses

What is Tamiflu® (oseltamivir) used for?

Tamiflu® is an antiviral medication that blocks the actions of influenza virus types A and B in your body.

Tamiflu® is used to treat influenza in people 2 weeks of age and older who have had flu symptoms for 2 days or less. Oseltamivir may also be given to prevent influenza in people who are at least 1year old, who may be exposed but do not yet have symptoms. Tamiflu® will not treat the common cold.

Tamiflu® may also be used for purposes not listed in this medication guide.

How should I take Tamiflu® (oseltamivir)?

Take Tamiflu® exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Start taking Tamiflu® as soon as possible after flu symptoms appear, such as fever, chills, muscle aches, sore throat, and runny or stuffy nose.

Take the capsule with a full glass of water.

Shake the oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

You may open the Tamiflu® capsule and sprinkle the medicine into a sweet liquid (corn syrup, chocolate syrup, brown sugar dissolved in water) to make swallowing easier. Swallow the mixture right away without chewing. Do not save for later use. Ask your doctor or pharmacist before using this method to prepare a Tamiflu® dose for a child who is younger than 13 years old or weighs less than 88 pounds.

Tamiflu® may be taken with food or milk if it upsets your stomach.

To treat flu symptoms: Take Tamiflu every 12 hours for 5 days.

To prevent flu symptoms: Take Tamiflu every 24 hours for 10 days or as prescribed. Follow your doctor’s instructions.

Use this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Tell your doctor if your symptoms do not improve, or if they get worse.

How do I store Tamiflu® (oseltamivir)?

Tamiflu® capsules

Tamiflu® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Tamiflu® in the bathroom or the freezer. There may be different brands of Tamiflu® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Tamiflu® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Tamiflu® liquid

Tamiflu® is best stored in the refrigerator. To prevent drug damage, do not freeze. There may be different brands of Tamiflu® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Tamiflu® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Tamiflu® (oseltamivir)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Tamiflu® or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You have received a nasal flu vaccine within the past 2 weeks.
  • You have kidney disease, heart disease, lung disease, or any other serious disease or health problem.
  • You have any condition causing swelling or disorder of the brain.

Tamiflu® should not be used in place of getting a yearly flu shot.

It is not known whether Tamiflu® is harmful to an unborn baby. However, not receiving this medication to prevent influenza could be harmful to the baby if the mother becomes infected with a disease that Tamiflu® could prevent. Tell your doctor if you are pregnant. Your doctor will decide whether you should receive this medicine.

It is not known whether oseltamivir passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breastfeeding a baby.

Do not use this medication to prevent influenza in a child younger than 1year old. Do not use this medication to treat influenza in a child younger than 2 weeks old.

Take Tamiflu® for as many days as it has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Tamiflu® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Tamiflu®. Tamiflu® is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Tamiflu® (oseltamivir)?

Common side effects may include:

Get emergency medical help if you have any of these signs of an allergic reaction to Tamiflu:

  • Chest pain or tightness
  • Difficult breathing
  • Fever, sore throat, swelling in your face or tongue, burning in your eyes
  • Hives, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling

Some people using Tamiflu® have had rare side effects of sudden confusion, shaking, problems with speech, hallucinations (hearing or seeing things that are not there), or seizure (convulsions). These symptoms have occurred most often in children, but it is not known whether Tamiflu® was the exact cause.

Anyone using Tamiflu® should be watched closely for signs of confusion or unusual behavior, especially a child.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Tamiflu® (oseltamivir)?

Tamiflu® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Tamiflu® (oseltamivir)?

Tamiflu® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Tamiflu® (oseltamivir)?

Tamiflu® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Health conditions that may interact with this drug are:

  • Kidney disease
  • Heart disease or chronic lung disease
  • A condition causing swelling or disorder of the brain
  • Weak immune system (caused by disease or by using certain medicine)
  • Hereditary fructose intolerance

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Tamiflu® (oseltamivir).

What is the dose of Tamiflu® (oseltamivir) for an adult?

Usual Adult Dose for Influenza:

The recommended dose is 75 mg orally twice a day for 5 days.

Approved indication: Treatment of acute, uncomplicated influenza infection in patients symptomatic no more than 48 hours.

Usual Adult Dose for Influenza Prophylaxis:

Following close contact with an infected individual: The recommended dose is 75 mg orally once a day for at least 10 days.

During a community outbreak of influenza: The recommended dose is 75 mg orally once a day.

What is the dose of Tamiflu® (oseltamivir) for a child?

Usual Pediatric Dose for Influenza:

2 weeks to less than 1 year: The recommended dose is 3 mg/kg orally twice a day.

1 through 12 years:

  • 15 kg or less: The recommended dose is 30 mg orally twice a day.
  • 1 through 23 kg: The recommended dose is 45 mg orally twice a day.
  • 1 through 40 kg: The recommended dose is 60 mg orally twice a day.
  • 1 kg or greater: The recommended dose is 75 mg orally twice a day.

13 years or older: The recommended dose is 75 mg orally twice a day.

Duration of therapy: 5 days.

Approved indication: Treatment of acute, uncomplicated influenza infection in patients (2 weeks or older) symptomatic no more than 48 hours.

Usual Pediatric Dose for Influenza Prophylaxis:

1 through 12 years:

  • 15 kg or less: The recommended dose is 30 mg orally once a day.
  • 1 through 23 kg: The recommended dose is 45 mg orally once a day.
  • 1 through 40 kg: The recommended dose is 60 mg orally once a day.
  • 1 kg or greater: The recommended dose is 75 mg orally once a day.

13 years or older: The recommended dose is 75 mg orally once a day.

Duration of therapy:

  • After close contact with an infected individual: 10 days.
  • During a community outbreak of influenza: May be continued for up to 6 weeks.

How is Tamiflu® (oseltamivir) available?

Tamiflu® is available in the following dosage forms and strengths:

  • Capsule; powder for suspension: Oseltamivir Phosphate 6mg in 1Ml

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Tamiflu®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

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