By Medically reviewed by Panel Perubatan Hello Doktor


What is Stilnox® (zolpidem tartrate) used for?

Stilnox® is commonly used for people who feel difficulty sleeping, called insomnia. It helps patients to initiate and maintain sleep and not recommended for use for more than 4 weeks at a time.

Stilnox® has a different chemical structure to other sleeping tablets. Stilnox® works by binding to special sites in the brain which produce sleep.

How should I take Stilnox® (zolpidem tartrate)?

  • Stilnox® should only be taken when you are able to get a full night’s sleep (7 to 8 hours) before you need to be active again. It should be taken in one dose and not be re-administered during the same night.
  • Swallow the tablet whole with a full glass of water, unless your doctor has told you to take half a tablet.
  • Usually, Stilnox® or any other medicines to treat sleeping disorders should only be used for short periods (e.g., 2 to 4 weeks). Continuous long-term use is not recommended unless advised by your doctor.
  • Ask your doctor or pharmacist if you are not sure how long to take the medicine.

How do I store Stilnox® (zolpidem tartrate)?

Stilnox® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Stilnox® in the bathroom or the freezer. There may be different brands of Stilnox® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Stilnox® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Stilnox® (zolpidem tartrate)?

Some people using this medicine have engaged in activity such as driving, eating, walking, making phone calls or having sex and later having no memory of the activity. If this happens to you, stop taking this medication and talk with your doctor about another treatment for your sleep disorder.

Do not take Stilnox® if you:

  • Drinking alcohol or you believe that you may have alcohol in your bloodstream.
  • Sleeping apnoea (a condition where you temporarily stop breathing while you sleep).
  • Myasthenia gravis (a condition in which the muscles become weak and tire easily).
  • Severe liver problems.
  • Acute and/or severe lung problems.

Do not take Stilnox® if you are allergic to Stilnox® or any inactive ingredients below:

  • Lactose;
  • Microcrystalline cellulose;
  • Hypromellose;
  • Sodium starch glycollate;
  • Magnesium stearate;
  • Titanium dioxide;
  • Macrogol 400;

Some symptoms of an allergic reaction include skin rash, itching, shortness of breath or swelling of the face, lips or tongue, which may cause difficulty in swallowing or breathing.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using this medication during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication. This medication is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk;
  • B=No risk in some studies;
  • C=There may be some risk;
  • D=Positive evidence of risk;
  • X=Contraindicated;
  • N=Unknown.

Side effects

What side effects can occur from Stilnox® (zolpidem tartrate)?

The most common side effects of this medicine:

  • Drowsiness;
  • Dizziness;
  • Headache;
  • Fatigue;
  • Worsened insomnia;
  • Nightmares;
  • Hallucinations;
  • Agitation;
  • Diarrhea, nausea, and vomiting;
  • Abdominal pain;
  • Muscle weakness;
  • Infections of the nose, throat and chest.

Less common adverse effects include:

  • Unexpected changes in behavior. These have included rage reactions, confusion, and others.
  • Sleep walking, other unusual, and some dangerous behaviors whilst apparently asleep. These have included preparing and eating food, making phone calls or having sexual intercourse. People experiencing these effects have had no memory of the events.


What drugs may interact with Stilnox® (zolpidem tartrate)?

Stilnox® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Some medicines may interfere with Stilnox®. These include:

  • Medicines to treat depression, anxiety and mental illness;
  • Medicines to treat epilepsy;
  • Pain relievers;
  • Muscle relaxants;
  • Antihistamines;
  • Medicines to treat infections, such as rifampicin or ciprofloxacin;
  • Ketoconazole, a medicine to treat antifungal infections.

Does food or alcohol interact with Stilnox® (zolpidem tartrate)?

Stilnox® may interact with food by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Stilnox® (zolpidem tartrate)?

Stilnox® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Tell your doctor if:

  • You have problems with your breathing or you often snore while you are asleep.
  • You have been addicted to alcohol, drug or medicine.
  • You have suffered from a mental illness.
  • You have medical conditions such as:
    • Liver, kidneys or lungs;
    • Epilepsy;
    • Depression;
    • Schizophrenia;
  • You plan to have surgery.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Stilnox® (zolpidem tartrate).

What is the dose of Stilnox® (zolpidem tartrate) for an adult?

  • The usual adult dose of Stilnox® is one tablet (10 mg).
  • If you are over 65 years old, the dose is half a Stilnox® tablet (5 mg).
  • If you have a liver problem, the usual recommended dose is half a Stilnox® tablet (5 mg). If necessary, this can be increased to 10 mg.
  • Your doctor may have prescribed a different dose. The lowest effective daily dose should be used and must not exceed 10 mg.

What is the dose of Stilnox® (zolpidem tartrate) for a child?

Stilnox® should not be given to children or adolescents less than 18 years of age.

How is Stilnox® (zolpidem tartrate) available?

Stilnox® is available in the following dosage forms and strengths:

  • Tablet 10mg.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services (115) or go to your nearest emergency room.

If you take too much Stilnox®, your consciousness may be impaired, ranging from drowsiness to light coma.

What should I do if I miss a dose?

If you forget to take the tablet before you go to bed, and you wake up late in the night or very early in the morning, do not take it.

If you are not sure what to do, ask your doctor.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: November 24, 2016 | Last Modified: December 19, 2019

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