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What is Stemetil® (prochlorperazine maleate) used for?

Stemetil® is commonly used for prevention and treatment of:

How should I take Stemetil® (prochlorperazine maleate)?

Use Stemetil® as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Stemetil® is usually given as an injection at your doctor’s office, hospital, or clinic. If you will be using Stemetil® at home, a health care provider will teach you how to use it. Be sure you understand how to use Stemetil®. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

Do not use Stemetil® if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

How do I store Stemetil® (prochlorperazine maleate)?

Stemetil® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Stemetil® in the bathroom or the freezer. There may be different brands of Stemetil® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Stemetil® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Stemetil® (prochlorperazine maleate)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Stemetil® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Stemetil® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Stemetil®.

Side effects

What side effects can occur from Stemetil® (prochlorperazine maleate)?

Check with your doctor if any of these most common side effects persist or become bothersome:

  • Agitation
  • Constipation
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Enlarged pupils
  • Jitteriness
  • Nausea
  • Stuffy nose

Seek medical attention right away if any of these severe side effects occur:

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest or throat; swelling of the mouth, face, lips, or tongue; unusual hoarseness; wheezing)
  • Confusion
  • Decreased coordination
  • Drooling
  • Fainting
  • Fast, slow, or irregular heartbeat
  • Mask-like face
  • Muscle spasms of the face, neck, or back
  • Muscle weakness
  • New or worsening mental or mood problems
  • Numbness of an arm or leg
  • Prolonged or painful erection
  • Restlessness
  • Seizures
  • Severe or persistent constipation
  • Severe or persistent dizziness, drowsiness, or headache
  • Shuffling walk
  • Sleeplessness
  • Stiff or rigid muscles
  • Sudden shortness of breath or vomiting
  • Swelling of the hands, ankles, or feet
  • Symptoms of infection (e.g., fever, chills, persistent sore throat)

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Stemetil® (prochlorperazine maleate)?

Stemetil® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug, such as:

  • Astemizole
  • Cabergoline
  • Cisapride
  • Dofetilide
  • Metoclopramide
  • Pergolide
  • Terfenadine
  • Tramadol
  • Alcohol or medicines that may cause drowsiness, such as barbiturates (eg, phenobarbital) or narcotic pain medicines (eg, codeine)

Does food or alcohol interact with Stemetil® (prochlorperazine maleate)?

Stemetil® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Stemetil® (prochlorperazine maleate)?

Stemetil® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Stemetil® (prochlorperazine maleate).

What is the dose of Stemetil® (prochlorperazine maleate) for an adult?

Prevention of nausea and vomiting

The recommended dose is 5 to 10 mg b.d. or t.d.s.

Treatment of nausea and vomiting

The recommended dose is 20 mg stat, followed if necessary by 10 mg two hours later.

Vertigo and Meniere’s syndrome

The recommended dose is 5 mg t.d.s. increasing if necessary to a total of 30 mg daily. After several weeks, dosage may be reduced gradually to 5-10 mg daily.

Adjunct in the short term management of anxiety

The recommended dose is 15-20 mg daily in divided doses initially but this may be increased if necessary to a maximum of 40 mg daily in divided doses.

Schizophrenia and other psychotic disorders

Usual effective daily oral dosage is in the order of 75-100 mg daily. Patients vary widely in response. The following schedule is suggested: Initially 12.5 mg twice daily for 7 days, the daily amount being subsequently increased 12.5 mg at 4 to 7 days interval until a satisfactory response is obtained. After some weeks at the effective dosage, an attempt should be made reduce this dosage. Total daily amounts as small as 50 mg or even 25 mg have sometimes been found to be effective.

What is the dose of Stemetil® (prochlorperazine maleate) for a child?

Prevention and treatment of nausea and vomiting

If it is considered unavoidable to use Stemetil® for a child, the dosage is 0.25 mg/kg bodyweight two or three a day. Stemetil® is not recommended for children weighing less than 10 Kg or below 1 year of age.

How is Stemetil® (prochlorperazine maleate) available?

Stemetil® is available in the following dosage forms and strengths:

  • Stemetil® 5 mg tablets

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Stemetil®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

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