By Medically reviewed by Hello Doktor Medical Panel


What is Pyridium® (phenazopyridine) used for?

Pyridium® is a pain reliever that affects the lower part of your urinary tract (bladder and urethra).

Pyridium® is used to treat pain, burning, increased urination and increased the urge to urinate. These symptoms are usually caused by infection, injury, surgery, catheter, or other conditions that irritate the lower urinary tract.

Pyridium® will treat the symptoms of a urinary tract infection, but this medication does not treat the actual infection. Take the antibiotic that your doctor prescribes to treat your infection.

Pyridium® may also be used for purposes other than those listed.

How should I take Pyridium® (phenazopyridine)?

Take Pyridium® exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take this medicine with a full glass of water. To avoid stomach upset, take Pyridium® with food.

Pyridium® will most likely darken the color of your urine to an orange or red color. This is a normal effect and is not cause for alarm unless you have other symptoms such as pale or yellowed skin, fever, stomach pain, nausea, and vomiting. Darkened urine may also cause stains to your underwear, which may or may not be removed by laundering.

Pyridium® can also permanently stain soft contact lenses, and you should not wear them while taking this medicine.

Do not use Pyridium® for longer than 2 days unless your doctor has told you to.

Pyridium® can cause you to have false results with glucose or ketone urine tests. Tell any doctor who treats you that you are using Pyridium®.

How do I store Pyridium® (phenazopyridine)?

Pyridium® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Pyridium® in the bathroom or the freezer. There may be different brands of Pyridium® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Pyridium® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Pyridium® (phenazopyridine)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Pyridium® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Do not take Pyridium® if you are allergic to phenazopyridine, or if you have kidney disease.

Before using Pyridium®, tell your doctor if you are allergic to any drugs, or if you have:

  • Liver disease
  • Diabetes
  • A condition called G6PD (glucose-6-phosphate dehydrogenase) deficiency

If you have any of these conditions, you may not be able to use Pyridium®, or you may need dosage adjustments or special tests during treatment.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Pyridium® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Pyridium®. Pyridium® is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Pyridium® (phenazopyridine)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Pyridium® and call your doctor at once if you have any of these serious side effects:

  • Pale skin, fever, confusion or weakness
  • Jaundice (yellowing of your skin or eyes)
  • Urinating less than usual or not at all
  • Drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting
  • Swelling, weight gain, feeling short of breath
  • Blue or purple coloring in your skin

Less serious side effects may include:

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Pyridium® (phenazopyridine)?

Pyridium® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Pyridium® (phenazopyridine)?

Pyridium® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Pyridium® (phenazopyridine)?

Pyridium® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Pyridium® (phenazopyridine).

What is the dose of Pyridium® (phenazopyridine) for an adult?

100 mg Tablets: Average adult dosage is two tablets 3 times a day after meals.

200 mg Tablets: Average adult dosage is one tablet 3 times a day after meals.

When used concomitantly with an antibacterial agent for the treatment of a urinary tract infection, the administration of Phenazopyridine HCl should not exceed 2 days.

What is the dose of Pyridium® (phenazopyridine) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Pyridium® (phenazopyridine) available?

Pyridium® is available in the following dosage forms and strengths:

  • Tablet, film coated: phenazopyridine hydrochloride 100mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Pyridium®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: August 21, 2017 | Last Modified: December 19, 2019

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