Know the basics
What is Ponstan® used for?
Ponstan® is commonly used for treating mild to moderate pain and menstrual pain (also known as dysmenorrhea).
How should I take Ponstan®?
Take Ponstan® by mouth with a full glass of water (240 ml) as directed by your doctor. It may be taken with food if it upsets your stomach but it may not lower the risk of stomach or bowel problems.
How do I store Ponstan®?
Ponstan® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Ponstan® in the bathroom or the freezer. There may be different brands of Ponstan® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush Ponstan® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Know the precautions & warnings
What should I know before using Ponstan®?
Do not use if:
- You are allergic to any ingredient in Ponstan®;
- You have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or a nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen, celecoxib);
- You have recently had or will be having bypass heart surgery;
- You have kidney problems, ulcers, or inflammation of the stomach or bowel;
- You are in the last 3 months of pregnancy.
Consult with your doctor if:
- You are pregnant, planning to become pregnant, or are breastfeeding;
- You are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement;
- You have allergies to medicines, foods, or other substances;
- You have a history of liver disease, diabetes, or stomach or bowel problem;
- You have a history of swelling or fluid buildup, asthma, growths in the nose, or mouth inflammation;
- You have high blood pressure, blood disorders, bleeding or clotting problems, heart problems, or blood vessel disease, or if you are at risk for any of these diseases;
- You have poor health, dehydration or low fluid volume, or low blood sodium levels, you drink alcohol, or you have a history of alcohol abuse.
Is it safe during pregnancy or breastfeeding?
There are no adequate studies in women for determining risk when using Ponstan® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Ponstan®. Ponstan® is pregnancy risk category C (D if used for prolonged periods) according to the US Food and Drug Administration (FDA).
FDA pregnancy risk category reference below:
- A=No risk;
- B=No risk in some studies;
- C=There may be some risk;
- D=Positive evidence of risk;
Know the side effects
What side effects can occur from Ponstan®?
Common side effects: stomach pain, nausea, vomiting, heartburn, constipation, diarrhea, rash, dizziness, ringing in your ear (tinnitus).
Serious side effects:
- Heart attack or stroke: chest pain, shortness of breath, weakness on one side of your body, slurred speech;
- Heart failure: unusual weight gain, swelling in your arms, legs, hands, or feet;
- Stomach problems: ulcers or bleeding;
- Liver problems: yellowing of your skin or whites of your eyes, flu-like symptoms, such as fever, chills, and body aches, tiredness, nausea, pain in the upper part of your stomach, itching;
- Skin reactions: reddening, blistering, or peeling skin;
- Allergic reactions: shortness of breath, swelling of your face, lips, or throat.
Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.
Know the interactions
What drugs may interact with Ponstan®?
Ponstan® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
- Ponstan® may reduce the effects of ACE inhibitors, such as captopril, enalapril, etc.
- Taking Ponstan® with methotrexate together may increase side effects of methotrexate.
- Magnesium hydroxide may increase Ponstan® levels in your body, which could increase its side effects.
- Ponstan® may increase the amount of lithium in your body, which could be toxic.
- Combining both warfarin, aspirin, ibuprofen, naproxen, and Ponstan® together increases your risk for serious stomach bleeding.
- Ponstan® can decrease the effectiveness of medications used to get rid of extra fluid in your body.
Does food or alcohol interact with Ponstan®?
Ponstan® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug. Combining alcohol with Ponstan® increases your risk of stomach bleeding or ulcer.
What health conditions may interact with Ponstan®?
Ponstan® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, such as:
- Liver disease, diabetes, or stomach or bowel problems;
- History of swelling or fluid buildup, asthma, growths in the nose, or mouth inflammation;
- High blood pressure, blood disorders, bleeding or clotting problems, heart problems, or blood vessel disease;
- Low fluid volume, or low blood sodium levels.
Understand the dosage
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Ponstan®.
What is the dose of Ponstan® for an adult?
- First dose: 500 mg;
- After that, take 250 mg every 6 hours as needed;
- You shouldn’t take mefenamic acid for longer than 7 days.
What is the dose of Ponstan® for a child?
Acute Pain by oral route
- <14 years old: not recommended;
- ≥14 years old: initial 500 mg once, then 250 mg every 6 hours; not exceed 7 days.
Primary Dysmenorrhea by oral route
- <14 years old: not recommended;
- ≥14 years old: initial 500 mg PO once, then 250 mg PO every 6 hours; not exceed 3 days.
How is Ponstan® available?
Ponstan® is available in the following dosage forms and strengths:
- Capsule 250mg;
- Tablet 500mg.
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services (115) or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of Ponstan®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Review Date: September 20, 2016 | Last Modified: December 19, 2019
Mefenamic acid. http://www.healthline.com/drugs/mefenamic-acid/oral-capsule#Dosage4. Accessed September 18, 2016.
Mefenamic acid. https://www.drugs.com/sfx/mefenamic-acid-side-effects.html. Accessed September 18, 2016.
Mefenamic acid. http://reference.medscape.com/drug/ponstel-mefenamic-acid-343294#6. Accessed September 18, 2016.