By Medically reviewed by Hello Doktor Medical Panel


What is Panadeine® (paracetamol and codeine) used for?

Panadeine® is used for the treatment of mild to moderate pain, diarrhea, cough, headache, toothache, ear pain and other conditions.

How should I take Panadeine® (paracetamol and codeine)?

Take Panadeine® by mouth and exactly as directed. Do not take more or less of it or take it more often than directed on the package label or recommended by your doctor.

How do I store Panadeine® (paracetamol and codeine)?

Panadeine® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Panadeine® in the bathroom or the freezer. There may be different brands of Panadeine® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Panadeine® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Panadeine® (paracetamol and codeine)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Panadeine® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Panadeine® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Panadeine®.

Side effects

What side effects can occur from Panadeine® (paracetamol and codeine)?

Side effects may occur when using this drug, such as:

  • Pain in the right side of your abdomen
  • Mental confusion
  • Hypersensitivity reactions
  • Blurred vision
  • High blood glucose level
  • Difficulty breathing
  • Hallucinations
  • Inflammation of the pancreas
  • Sweating
  • Difficulty or pain in passing urine
  • Enlarged spleen or swollen or enlarged lymph nodes
  • Sensation of spinning
  • Facial flushing
  • Drowsiness
  • Constipation
  • Feeling sick or being sick
  • Loss of appetite
  • Feeling unwell
  • Hypothermia
  • Dizziness
  • Fever
  • Nightmares
  • Dry mouth
  • Stomach cramps
  • Headache
  • Depression
  • Sadness

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Panadeine® (paracetamol and codeine)?

Panadeine® (paracetamol and codeine) may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug include:

  • Anaesthetics
  • Antipsychotics
  • Anxiolytics
  • Cisapride
  • Cyclizine
  • Domperidone
  • Hypnotics
  • Interfere with certain laboratory tests
  • Juxtapid mipomersen
  • Ketoconazole
  • Leflunomide
  • Metoclopramide
  • Mexiletine
  • Monoamine oxidase inhibitors

Does food or alcohol interact with Panadeine® (paracetamol and codeine)?

Panadeine® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Panadeine® (paracetamol and codeine)?

Panadeine® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Panadeine® (paracetamol and codeine).

What is the dose of Panadeine® (paracetamol and codeine) for an adult?

Usual dose is 1 tablet 4 hourly or as needed.

What is the dose of Panadeine® (paracetamol and codeine) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Panadeine® (paracetamol and codeine) available?

Panadeine® is available in the following dosage forms and strengths:

  • Tablet

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Panadeine®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

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Review Date: August 11, 2017 | Last Modified: December 19, 2019

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