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What is Oxytrol® (oxybutynin) used for?

Oxytrol® is commonly used to reduce muscle spasms of the bladder and urinary tract.

Oxytrol® transdermal skin patch is used to treat symptoms of an overactive bladder such as frequent or urgent urination, incontinence (urine leakage), and increased nighttime urination.

Oxytrol® patches may also be used for purposes not listed in this medication guide.

How should I take Oxytrol® (oxybutynin)?

Use Oxytrol® skin patches exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Oxytrol® comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Open the sealed pouch and remove the protective liner. Apply the Oxytrol® patch to a clean, dry area on your stomach, hip or buttock. Avoid skin that is oily, irritated, or damaged. Avoid placing the patch on a skin area that will be rubbed by a waistband or tight clothing.

Press the Oxytrol® patch firmly into place with your fingers. You may leave the patch on while bathing, showering, or swimming.

If an Oxytrol® patch falls off, try sticking back into place. If it does not stick well, put on a new patch and leave it on only for the rest of your wearing time. Do not change your patch removal schedule.

Leave the Oxytrol® patch in place and wear it for 3 to 4 days. You should change the patch twice per week (such as every Sunday and Thursday). Use a calendar to help you keep a steady patch-changing schedule.

Choose a different place on your skin to wear the patch each time you put on a new one. Do not use the same skin area twice within 7 days.

Do not wear more than one Oxytrol® patch at a time. Using extra skin patches will not make the medicine more effective. Never cut a skin patch.

Use baby oil or mild soap and water to remove any adhesive residue that stays on your skin. Avoid using harsh soaps, alcohol, nail polish remover, or other solvents that could irritate your skin.

After removing a patch, fold it in half so it sticks together and throw it away in a place where children or pets cannot get to it.

The Oxytrol® patch may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the patch before undergoing such a test.

How do I store Oxytrol® (oxybutynin)?

Oxytrol® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Oxytrol® in the bathroom or the freezer. There may be different brands of Oxytrol® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Oxytrol® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Oxytrol® (oxybutynin)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Oxytrol® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

You should not use Oxytrol® skin patches if you have:

  • Untreated or uncontrolled narrow-angle glaucoma
  • A blockage in your digestive tract (stomach or intestines)
  • If you have decreased urination or are unable to urinate

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Oxytrol® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Oxytrol®. Oxytrol® is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Oxytrol® (oxybutynin)?

Get emergency medical help if you have any signs of an allergic reaction to Oxytrol®: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Oxytrol® patches and call your doctor at once if you have:

  • Little or no urinating
  • Severe constipation
  • Confusion, hallucinations
  • Vomiting, severe heartburn or upper stomach pain
  • Fast or uneven heart rate
  • Dehydration symptoms – feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin

Common side effects may include:

  • Dizziness, drowsiness
  • Redness or mild skin itching where a patch was worn
  • Dry mouth
  • Blurred vision
  • Constipation, diarrhea

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Oxytrol® (oxybutynin)?

Oxytrol® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • Cold or allergy medicine that contains an antihistamine
  • Medicine for Parkinson’s disease
  • Medicine to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome
  • Bronchodilators–aclidinium, ipratropium, or tiotropium
  • Medicine to treat osteoporosis or Paget’s disease of bone–alendronate, etidronate, ibandronate, pamidronate, risedronate, tiludronate, zoledronic acid
  • Other bladder or urinary medicines–darifenacin, fesoterodine, oral oxybutynin, tolterodine, solifenacin

Does food or alcohol interact with Oxytrol® (oxybutynin)?

Oxytrol® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Oxytrol® (oxybutynin)?

Oxytrol® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Health conditions that may interact with this drug are:

  • Glaucoma
  • Liver or kidney disease
  • Myasthenia gravis
  • An enlarged prostate
  • An intestinal disorder, such as ulcerative colitis
  • A stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion
  • If you have trouble emptying your bladder


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Oxytrol® (oxybutynin).

What is the dose of Oxytrol® (oxybutynin) for an adult?

Oxytrol® 3.9 mg/day should be applied to dry, intact skin on the abdomen, hip, or buttock twice weekly (every 3 or 4 days). A new application site should be selected with each new system to avoid re-application to the same site within 7 days.

What is the dose of Oxytrol® (oxybutynin) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Oxytrol® (oxybutynin) available?

Oxytrol® is available in the following dosage forms and strengths:

  • Patch: oxybutynin 3.9mg in 1d

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Oxytrol®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

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