Maninil 5

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Kemas kini Tarikh 12/05/2020 . 5 minit bacaan
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What is Maninil® 5 (glibenclamide) used for?

Maninil® 5 is commonly used for non-insulin-dependent diabetes mellitus (type 2 diabetes mellitus in adults), when you cannot achieve metabolic control with diet, physical activity and reduction of body teglo.

How should I take Maninil® 5 (glibenclamide)?

Taking Maninil® 5 with sufficient liquid, once in the morning before breakfast.

If the dose is 3 tablets, they can take 2 tablets in the morning one night.

It is important to take the tablets at the same time each day. If a dose is missed, it should be administered later than 1-2 hours after the scheduled time – better to miss doses.

The next regular intake is at the appointed time. Missed doses should never be compensated by taking more tablets or apply later drug. When taking the medicine must not skip meals.

How do I store Maninil® 5 (glibenclamide)?

Maninil® 5 is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Maninil® 5 in the bathroom or the freezer. There may be different brands of Maninil® 5 that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Maninil® 5 down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Maninil® 5 (glibenclamide)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Maninil® 5 or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Maninil® 5 lowers blood sugar. Treatment with this medication requires regular medical supervision.

Overdose diet errors (skipping a meal or insufficient intake of food), excessive alcohol consumption, unusual physical exertion may occur severely low blood sugar (hypoglycemia). Signs of low blood sugar are sudden sweating, palpitations, trembling, hunger, nervousness, tingling around the mouth, pallor, headache, dizziness, sleep disturbances, anxiety, depressed mood, unstable movements, impaired speech and vision, paralysis symptoms. Strong decrease of blood glucose can lead to helplessness, loss of consciousness and seizures.

Diabetic patient may adjust slightly decrease blood sugar by eating sugar or foods rich in sugar. Here’s why you should always carry an 20 g of glucose.

If there is a severe decrease in blood sugar with loss of consciousness, an urgent need to call a doctor.

Caution is required in elderly patients, patients with impaired hepatic and / or renal function, decreased function of the thyroid gland, pituitary or adrenal gland, patients who forget or in patients who do not comply with the recommendations for diet and use of medicines, since they are at high risk for a decrease in blood glucose levels.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using this medication during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication.

Side effects

What side effects can occur from Maninil® 5 (glibenclamide)?

Usually Maninil® 5 is well – tolerated. At the start of treatment, it may temporarily appear visual disturbances. Rarely, occurring gastrointestinal disorders and allergic reactions, particularly of the skin (very rare, including reports of serious side effects). In isolated cases, bleeding disorders have been observed.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Maninil® 5 (glibenclamide)?

Maninil® 5 may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Maninil® 5 (glibenclamide)?

Maninil® 5 may interact with food by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Maninil® 5 (glibenclamide)?

Maninil® 5 may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Maninil® 5 (glibenclamide).

What is the dose of Maninil® 5 (glibenclamide) for an adult?

Dosage adjustment in diabetics should be performed only by a doctor and with proper diet. The dose depends on the results of studies of metabolism (sugar in the blood and urine).

At the beginning of treatment, doctor recommends increase the dose. Treatment begins with 1/2 tablet once a day and gradually increased to the required dose at intervals of several days.

The maximum effect is achieved with 3 tablets daily.

What is the dose of Maninil® 5 (glibenclamide) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Maninil® 5 (glibenclamide) available?

Maninil® 5 is available in the following dosage forms and strengths:

  • Maninil® 5 tablets 5mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services (or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Maninil® 5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

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