By Medically reviewed by Hello Doktor Medical Panel


What is Hyperium® (Rilmenidine Phosphate) used for?

Hyperium® is commonly used for the treatment of hypertension.

How should I take Hyperium® (Rilmenidine Phosphate)?

This drug should be taken on an empty stomach (before meals).

How do I store Hyperium® (Rilmenidine Phosphate)?

Hyperium® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Hyperium® in the bathroom or the freezer. There may be different brands of Hyperium® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Hyperium® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Hyperium® (Rilmenidine Phosphate)?

Before using this drug, you should know that:

  • Therapy should never be interrupted suddenly; the dosage should be reduced gradually.
  • Using Hyperium® may affect on the ability to drive or operate machinery.

Is it safe during pregnancy or breastfeeding?


Hyperium® should be avoided in pregnant women, although no teratogenic or embryotoxic effects have been observed in animal studies.


Hyperium® is excreted in breast milk, and its use is therefore not recommended during lactation.

Side effects

What side effects can occur from Hyperium® (Rilmenidine Phosphate)?

Some side effects can occur while using this drug, including:

  • Asthenia
  • Palpitations
  • Insomnia
  • Drowsiness
  • Fatigue on exercise
  • Epigastric pain
  • Dryness of the mouth
  • Diarrhea
  • Skin rash
  • Cold extremities
  • Postural hypotension
  • Sexual disorders
  • Anxiety
  • Depression
  • Pruritus
  • Edema
  • Cramps
  • Nausea
  • Constipation
  • Hot flushes

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Hyperium® (Rilmenidine Phosphate)?

Hyperium® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug, including:

  • MAOIs
  • Tricyclic antidepressants

Does food or alcohol interact with Hyperium® (Rilmenidine Phosphate)?

Hyperium® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Hyperium® (Rilmenidine Phosphate)?

Hyperium® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Hyperium® (Rilmenidine Phosphate).

What is the dose of Hyperium® (Rilmenidine Phosphate) for an adult?

The recommended dosage is one tab/day as a single morning administration.

If results are not adequate after 1 month of treatment, the dosage may be increased to two tabs/day, given in divided doses (1 tab in the morning and in the evening) before meals.

Treatment may be continued indefinitely.

What is the dose of Hyperium® (Rilmenidine Phosphate) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Hyperium® (Rilmenidine Phosphate) available?

Hyperium® is available in the following dosage forms and strengths:

  • Tablets; Rilmenidine Phosphate 1 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Hyperium®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: February 7, 2017 | Last Modified: December 19, 2019

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