By Medically reviewed by Hello Doktor Medical Panel


What is hordenine used for?

Hordenine is a chemical naturally found in barley (Hordeum vulgare). It is similar in chemical structure to stimulants found in bitter orange. It can also be found in algae, cacti, and some grass species.

People take hordenine by mouth for improving athletic performance and weight loss.

How does it work?

There are not enough studies about how hordenine works. Please discuss with your herbalist or doctor for more information. However, some research shows that it might stimulate the central nervous system, and increase heart rate, blood pressure, and breathing rate. These effects seem to be short-lived and require high doses.

Precautions & warnings

What should I know before using hordenine?

Consult with your doctor or pharmacist or herbalist, if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription.
  • You have allergy with any substances of hordenine or other medications or other herbs.
  • You have any other illnesses, disorders, or medical conditions.
  • You have any other types of allergies, such as to foods, dyes, preservatives, or animals.

The regulations for an herbal supplement are less strict than the regulations for a drug. More studies are needed to determine its safety. The benefits of taking this herbal supplement must outweigh the risks before use. Consult with your herbalist or doctor for more information.

How safe is hordenine?

Hordenine is possibly unsafe when taken by mouth.

Special precautions & warnings

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking hordenine if you are pregnant or breast feeding. Stay on the safe side and avoid use.

High blood pressure: Hordenine is similar to stimulants found in bitter orange. In theory, taking hordenine might make high blood pressure worse.

Kidney stones: Taking hordenine might increase the risk for kidney stones.

Surgery: Hordenine might interfere with surgery by increasing blood pressure and heart rate. Stop taking hordenine at least 2 weeks before surgery.

Side effects

What kind of side effects may I have from hordenine?

In theory, hordenine might have similar stimulant effects and side effects such as rapid heart rate and high blood pressure. Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about side effects, please consult your herbalist or doctor.


What interactions may I have with hordenine?

Hordenine may interact with your current medications or medical conditions. Consult with your herbalist or doctor before using.


The information provided is not a substitute for medical advice. ALWAYS consult your herbalist or doctor before using this medication.

What is the usual dose for hordenine?

The dose for hordenine may be different for every patient. The dose that you take depends on your age, health, and several other conditions. Herbal supplement are not always safe. Please discuss with your herbalist or doctor for your appropriate dosage.

What form does hordenine come in?

Hordenine may be available in the following dosage forms:

  • Encapsulated hordenine
  • Hordenine hcl powder

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: August 15, 2017 | Last Modified: December 4, 2019

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