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Leuprolide is a gonadotropin-releasing hormone (GnRH) agonist. It works by decreasing levels of certain hormones produced by the testes and ovaries. This prevents the growth of certain tumors that need these hormones to grow.
Enantone LP is commonly used for treating symptoms of advanced prostate cancer. It may also be used for other conditions as determined by your doctor.
Use enantone LP as directed by your doctor. Ask your health care provider any questions you may have about how to use enantone LP.
Enantone LP is usually given every month (4 weeks) as an injection at your doctor’s office, hospital, or clinic. If you will be using leuprolide at home, a health care provider will teach you how to use it. Be sure you understand how to use leuprolide. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
Do not use enantone LP if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
Enantone LP is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store enantone LP in the bathroom or the freezer. There may be different brands of enantone LP that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush enantone LP down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Before using enantone LP, tell your doctor if:
Also, there is some important information that you may notice:
There are no adequate studies in women for determining risk when using this enantone LP during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking enantone LP. Enantone LP is pregnancy risk category X, according to the US Food and Drug Administration (FDA).
FDA pregnancy risk category reference below:
Lactation:
Contraindicated; not known if drug is excreted in breast milk; make decision to either discontinue nursing or discontinue drug, taking into account risk and benefits to the mother.
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome:
Seek medical attention right away if any of these severe side effects occur:
Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.
Enantone LP may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Products may interact with your drug, including:
Enantone LP may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
Enantone LP may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.
Especially if you have:
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using enantone LP (leuprolide).
Prostate cancer
The recommended dose is one 3.75-mg DPS monthly, or one 11.25-mg DPS every 3 months as a single SC/IM inj.
Endometriosis
The recommended dose is one 3.75-mg DPS monthly, or one 11.25-mg DPS every 3 month as a single SC/IM inj.
Patient <50 kg
The recommended dose is 1.88-mg DPS monthly. Start during the 1st 5 days of the menstrual cycle. Duration: 6 months, can be used for 12 months w/ concurrent HRT (norethindrone acetate 5 mg daily).
Uterine fibroids
The recommended dose is one 1.88-mg DPS monthly, or 3.75-mg DPS for patients w/ heavy wt or markedly enlarged uterus, for 3 months, or one 11.25-mg DPS as single SC/IM inj.
Breast cancer
The recommended dose is one 3.75-mg DPS monthly as a single SC/IM inj.
Central precocious puberty
The recommended dose is 3.75-mg DPS 90-400 mcg/kg SC/IM monthly. Dose adjusted according to patient’s response.
Central Precocious Puberty
Indicated when signs of sexual maturity begin to develop in girls <8 years old and boys <9 years old; may be discontinued at appropriate age of onset of puberty (e.g., 11 years in females and 12 years in males), at physician’s discretion.
<2 years old: Safety and efficacy not established.
Lupron Depot-Ped (monthly dose)
Lupron Depot-Ped (3-month dose)
Leuprolide acetate
Enantone LP is available in the following dosage forms and strengths:
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
If you miss a dose of enantone LP, contact your doctor right away.
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