By Medically reviewed by Panel Perubatan Hello Doktor


What is Calmol® (acetaminophen) used for?

Calmol® is a pain reliever and a fever reducer. It is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It relieves pain in mild arthritis but has no effect on the underlying inflammation and swelling of the joint.

Calmol® may also be used for other purposes, ask your doctor for more information.

How should I take Calmol® (acetaminophen)?

Calmol® chewable tablet must be chewed thoroughly before you swallow it. Make sure your hands are dry when handling the Calmol® disintegrating tablet. Place the tablet on your tongue. It will begin to dissolve right away. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

To use the Calmol® effervescent granules, dissolve one packet of the granules in at least 110ml of water. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

Do not take a Calmol® rectal suppository by mouth. It is for use only in your rectum. Wash your hands before and after inserting the suppository.

Try to empty your bowel and bladder just before using the Calmol® suppository. Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.

For best results from the suppository, lie down and insert the suppository pointed tip first into the rectum. Hold in the suppository for a few minutes. It will melt quickly once inserted and you should feel little or no discomfort while holding it in. Avoid using the bathroom just after inserting the suppository.

How do I store Calmol® (acetaminophen)?

Calmol® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Calmol® in the bathroom or the freezer. There may be different brands of Calmol® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Calmol® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Calmol® (acetaminophen)?

Before using this drug, tell your doctor if you are allergic to acetaminophen or Calmol®.

Also, you should notice that:

  • Urine glucose tests may produce false results while you are taking Calmol®. Talk to your doctor if you are diabetic and you notice changes in your glucose levels during treatment.
  • Do not use this medication without first talking to your doctor if you drink more than three alcoholic beverages per day or if you have had alcoholic liver disease (cirrhosis). You may not be able to use Calmol®.
  • Do not use any other over-the-counter cough, cold, allergy, or pain medication without first asking your doctor or pharmacist. Calmol® is contained in many combination medicines. If you use certain products together you may accidentally use too much Calmol®. Read the label of any other medicine you are using to see if it contains Calmol®, acetaminophen or APAP.
  • Avoid drinking alcohol while taking this medication. Alcohol may increase your risk of liver damage while taking Calmol®.
  • Using more Calmol® could cause damage to your liver.

Stop using Calmol® and call your doctor if:

  • You still have a fever after 3 days of use.
  • You still have pain after 7 days of use (or 5 days if treating a child).
  • You have a skin rash, ongoing headache, or any redness or swelling.
  • Your symptoms get worse, or if you have any new symptoms.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Calmol® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Calmol®.

Side effects

What side effects can occur from Calmol® (acetaminophen)?

Get emergency medical help if you have any of these signs of an allergic reaction to Calmol® such as hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • Low fever with nausea, stomach pain, and loss of appetite
  • Dark urine
  • Clay-colored stools
  • Jaundice (yellowing of the skin or eyes)

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Calmol® (acetaminophen)?

Calmol® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

A product that may interact with this drug is ketoconazole. This medication may interfere with certain laboratory tests, possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Does food or alcohol interact with Calmol® (acetaminophen)?

Calmol® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Calmol® (acetaminophen)?

Calmol® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Ask a doctor or pharmacist if it is safe for you to take Calmol® if you have:

  • Liver disease
  • A history of alcoholism


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Calmol® (acetaminophen).

What is the dose of Calmol® (acetaminophen) for an adult?


The recommended dose is 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours orally or rectally.


The recommended dose is 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours orally or rectally.

The maximum amount for adults is 1 gram (1000 mg) per dose and 4 grams (4000 mg) per day. If you drink more than three alcoholic beverages per day, talk to your doctor before taking Calmol® and never use more than 2 grams (2000 mg) per day.

What is the dose of Calmol® (acetaminophen) for a child?

The dosage has not been established in pediatric patients under 2 years old. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Calmol® (acetaminophen) available?

Calmol® is available in the following dosage forms and strengths:

  • Capsules
  • Extended-release tablets
  • Film-coated tablets
  • The suspension
  • Solution package to phase

What should I do in case of an emergency or overdose?

An overdose of Calmol® can cause serious harm. The first signs of overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Calmol®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: March 18, 2017 | Last Modified: December 19, 2019

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