Advil PM (Sleep Aids)

By Medically reviewed by Hello Doktor Medical Panel


What is Advil® PM used for?

Advil® PM is commonly used for treating minor aches and pains that may cause sleeplessness.

How should I take Advil® PM?

Take Advil® PM by mouth with or without food. It may be taken with food if it upsets your stomach. Taking it with food may not lower the risk of stomach or bowel problems (e.g., bleeding, ulcers). Talk with your doctor or pharmacist if you have persistent stomach upset.

Take Advil® PM with a full glass of water (8 oz/240 mL) as directed by your doctor.

Do not take Advil® PM unless you have time for a full night of sleep.

How do I store Advil® PM?

Advil® PM is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Advil® PM in the bathroom or the freezer. There may be different brands of Advil® PM that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Advil® PM down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Advil® PM?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Advil® PM or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You have had a severe allergic reaction (e.g., severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or an NSAID (e.g., ibuprofen, celecoxib).
  • You have recently had or will be having bypass heart surgery.
  • You are taking or have taken a monoamine oxidase inhibitor (MAOI) (e.g., phenelzine) in the past 14 days, or you are taking sodium oxybate (GHB).
  • You are dehydrated, drink alcohol, or have a history of alcohol abuse.
  • You have poor health or sleeplessness without pain, or if you are older than 60 years old.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Advil® PM during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Advil® PM.

Side effects

What side effects can occur from Advil® PM?

Common side effects are:

  • Constipation
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dry mouth, throat, and nose
  • Excitability
  • Gas
  • Headache
  • Heartburn
  • Nausea
  • Stomach pain or upset
  • Thickening of mucus in nose or throat

Seek medical attention right away if any of these severe side effects occur:

  • Rash
  • Hives
  • Itching
  • Trouble breathing
  • Tightness in the chest
  • Swelling of the mouth, face, lips, or tongue

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Advil® PM?

Advil® PM may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Some products may interact with this drug, including:

  • Lithium
  • Methotrexate
  • A blood thinner (warfarin, Coumadin, Jantoven)
  • Heart or blood pressure medication, including a diuretic or “water pill”
  • Steroid medicine (such as prednisone)

Does food or alcohol interact with Advil® PM?

Advil® PM may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Advil® PM?

Advil® PM may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • A history of kidney or liver disease
  • Diabetes
  • Stomach or bowel problems (e.g., bleeding, perforation, ulcers, persistent or returning stomach pain or heartburn)
  • A history of swelling or fluid buildup
  • Lupus
  • Growths in the nose (nasal polyps)
  • Mouth inflammation
  • High blood pressure
  • Blood disorders (e.g., porphyria)
  • Bleeding or clotting problems
  • Heart problems (e.g., heart failure)
  • Blood vessel disease
  • Asthma
  • Chronic obstructive pulmonary disease (COPD)
  • Chronic bronchitis
  • Emphysema
  • Lung disease
  • Shortness of breath
  • Sleep apnea
  • Blockage of the stomach, intestine, or urinary tract
  • Difficulty urinating
  • Ulcers
  • Enlargement of the prostate or other prostate problems
  • Glaucoma or increased eye pressure
  • Thyroid disease
  • Low blood sodium levels
  • Low fluid volume (e.g., caused by diarrhea, vomiting, not drinking fluids)


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Advil® PM.

What is the dose of Advil® PM for an adult?

38 mg-200 mg oral tablet: 2 tablets orally at bedtime not to exceed 2 tablets daily.

25 mg-200 mg oral capsule: 2 capsules orally at bedtime not to exceed 2 capsules daily.

What is the dose of Advil® PM for a child?

38 mg-200 mg oral tablet:

12 yrs or older: 2 tablets orally at bedtime not to exceed 2 tablets daily.

25 mg-200 mg oral capsule:

12 yrs or older: 2 capsules orally at bedtime not to exceed 2 capsules daily.

How is Advil® PM available?

Advil® PM is available in the following dosage forms and strengths:

  • Tablet
  • Capsule

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Advil® PM, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

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Review Date: June 2, 2017 | Last Modified: December 19, 2019

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