By Medically reviewed by Hello Doktor Medical Panel


What is Abetol® (labetalol hydrochloride) used for?

Abetol® is commonly used for lowering high blood pressure to prevent strokes, heart attacks, and kidney problems.

Abetol® may be prescribed for other uses; ask your doctor or pharmacist for more information.

How should I take Abetol® (labetalol hydrochloride)?

Take Abetol® by mouth, as directed by your doctor. You may take this medication with or without food.

To decrease the risk of side effects, this medication will be used at a low dose and gradually increase your dose. Follow your doctor’s instructions carefully.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

How do I store Abetol® (labetalol hydrochloride)?

Abetol® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Abetol® in the bathroom or the freezer. There may be different brands of Abetol® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Abetol® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Abetol® (labetalol hydrochloride)?

Consult with your doctor or pharmacist, if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Abetol® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Abetol® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Abetol®. Abetol® is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Abetol® (labetalol hydrochloride)?

Abetol® may cause following side effects, such as:

  • Dizziness
  • Tingling scalp or skin
  • Lightheadedness
  • Excessive tiredness
  • Headache
  • Upset stomach
  • Stuffy nose
  • Shortness of breath or wheezing
  • Swelling of the feet and lower legs
  • Sudden weight gain
  • Chest pain

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Abetol® (labetalol hydrochloride)?

Abetol® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug, such as:

  • Taking labetalol with a tricyclic antidepressant may increase your risk of tremors. These drugs include amitriptyline; doxepin; nortriptyline; clomipramine.
  • Taking labetalol may cause narrowing of your airways. This may make it harder for you to breathe. Your doctor may increase your dose of asthma medications. These drugs include albuterol; salmeterol; aformoterol; indacaterol; olodaterol.
  • Heartburn medications can cause the amount of labetalol in your body to increase. This can cause more side effects. These drugs include cimetidine.
  • Taking labetalol with certain medications for the heart may cause you to have very low blood pressure and heart rate. These drugs include nitroglycerin; digoxin; clonidine; amiodarone; disopyramide; calcium channel blockers.

Does food or alcohol interact with Abetol® (labetalol hydrochloride)?

Abetol® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Abetol® (labetalol hydrochloride)?

Abetol® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Especially for those patients who have these medical conditions:

  • Diabetes
  • An adrenal gland tumor (pheochromocytoma)
  • Lung or breathing problems (e.g., bronchitis, chronic obstructive pulmonary disease [COPD], emphysema)
  • Kidney problems
  • Liver problems
  • Thyroid problems
  • Heart problems (e.g., first-degree heart block, slow heartbeat, irregular heartbeat, Wolff-Parkinson-White syndrome, sick sinus syndrome)
  • Low blood pressure
  • A history of heart failure
  • A recent heart attack


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.

What is the dose of Abetol® (labetalol hydrochloride) for an adult?

Adult dosage (ages 18–64 years)

Initial dose: 100 mg taken by mouth two times per day.

Maintenance dose: 200–400 mg taken two times per day. If needed, your doctor may increase your dose every 2–3 days.

Maximum dose: 2400 mg per day taken in 2–3 divided doses.

What is the dose of Abetol® (labetalol hydrochloride) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug using. Please consult with your doctor or pharmacist for more information.

How is Abetol® (labetalol hydrochloride) available?

Abetol® is available in the following dosage forms and strengths:

  • Oral tablets 100mg
  • Oral tablets 200mg
  • Oral tablets 300mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Abetol®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Review Date: May 25, 2017 | Last Modified: December 19, 2019

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