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What is Duofilm® (salicylic acid) used for?

Duofilm® is commonly used to treat skin or foot with warts, corns, and calluses. This product should not be used on the face or on moles, birthmarks, warts with hair growing from them, or genital/anal warts.

Salicylic acid is a keratolytic. It belongs to the class of drugs as aspirin (salicylates). It works by increasing the amount of moisture in the skin and dissolving the substance that causes the skin cells to stick together. This makes it easier to shed the skin cells. Warts are caused by a virus. Salicylic acid does not affect the virus.

How should I take Duofilm® (salicylic acid)?

Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

This medication is for use on the skin only. To avoid irritation, do not let this medication come into contact with your eyes, nose, mouth, groin, or any broken skin. If you do get the medication in those areas, flush the area with cool water for 15 minutes. Wash hands after use.

These steps are:

  • Wash affected area;
  • May soak wart in warm water for 5 minutes;
  • Dry thoroughly;
  • Apply one drop at a time with applicator to sufficiently cover each wart;
  • Let dry;
  • Self-adhesive cover-up discs may be used to conceal wart;
  • Repeat procedure once or twice daily as needed (until wart is removed) for up to 12 weeks.

How do I store Duofilm® (salicylic acid)?

Duofilm® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Duofilm® in the bathroom or the freezer. There may be different brands of Duofilm® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Duofilm® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Duofilm® (salicylic acid)?

Before using salicylic acid, tell your doctor or pharmacist if you are allergic to it; or to nonsteroidal anti-inflammatory drugs-NSAIDs (e.g., aspirin, ibuprofen, naproxen); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Do not give this medication to a child or teenager with a fever, flu symptoms, or chicken pox. Salicylic acid can cause Reye’s syndrome, a serious and sometimes fatal condition in children.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using this medication during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication. This medication is pregnancy risk category C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk;
  • B=No risk in some studies;
  • C=There may be some risk;
  • D=Positive evidence of risk;
  • X=Contraindicated;
  • N=Unknown.

Side effects

What side effects can occur from Duofilm® (salicylic acid)?

  • Slight burning, skin redness, and peeling may occur. These effects are expected. If any of these effects worsen, tell your doctor or pharmacist promptly. If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
  • Tell your doctor right away if there are serious side effects (spreading skin redness around the treated area, signs of infection, formation of a deep sore at the treatment site) or serious allergic reaction (rash, itching/swelling of the face/tongue/throat, severe dizziness, trouble breathing).

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.


What drugs may interact with Duofilm® (salicylic acid)?

Duofilm® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Before using this product, tell your doctor or pharmacist if you use other products used on the treated skin.

Does food or alcohol interact with Duofilm® (salicylic acid)?

Duofilm® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Duofilm® (salicylic acid)?

Duofilm® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Especially, ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions, such as:


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Duofilm® (salicylic acid).

What is the dose of Duofilm® (salicylic acid) for an adult?

Dosage is based on your medical condition, product type/brand, and response to treatment. Do not use large amounts, apply this medication more often, or use it for a longer period than directed. Your condition will not clear faster, but the chance for side effects may be increased.

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

What is the dose of Duofilm® (salicylic acid) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Duofilm® (salicylic acid) available?

Duofilm® is available in the following dosage forms and strengths:

  • Salicylic acid 150.28mg in 1ml.
  • 8 ml bottle carton liquid.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services (115) or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Duofilm®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

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