Duodart puts two prostate medicines in one daily capsule: dutasteride 0.5mg to shrink an enlarged prostate and tamsulosin 0.4mg to ease the flow within days. RM299 for 30 capsules, checked by a licensed doctor before it is sent.
Duodart is a once daily prescription capsule for benign prostatic hyperplasia (BPH), the non-cancerous enlargement of the prostate that affects many men over 50. It combines two medicines that work in different ways, so one capsule replaces two separate pills. For men who would otherwise need both, that means one less thing to remember each day.
Dutasteride 0.5mg
Blocks the conversion of testosterone into DHT, the hormone that drives prostate growth. Over months the prostate gets smaller, which treats the cause of the blockage.
Tamsulosin 0.4mg
An alpha blocker that relaxes the muscle in the prostate and at the bladder neck. It eases the flow within days, while the dutasteride is still working.
Duodart uses
Duodart is registered in Malaysia for men with BPH. Doctors prescribe it to:
Ease moderate to severe urinary symptoms of an enlarged prostate: a weak or interrupted stream, straining, urgency and getting up at night
Lower the long-term risk of acute urinary retention, when you suddenly cannot pass urine
Lower the chance of needing prostate surgery
It is usually chosen when the prostate is clearly enlarged and symptoms are bothersome enough that one medicine alone may not be enough. In large clinical trials, taking the two together lowered the risk of symptoms getting worse more than either medicine on its own. Duodart does not treat prostate cancer, erection problems or hair loss.
What to expect on Duodart
The two medicines work on different timelines: one quickly, one slowly. Here is what most men notice.
1
First 1 to 2 weeks
The tamsulosin part relaxes the prostate, so many men notice an easier, stronger flow. Some feel light headed when standing up early on.
2
1 to 3 months
Dutasteride lowers DHT and the prostate starts to shrink. Night-time trips often begin to settle.
3
6 months
The usual point for your doctor to review progress. PSA is now about half its earlier level, which is expected.
4
Long term
Both effects last while you keep taking it daily. Your doctor will check your symptoms and PSA at regular reviews.
How to take Duodart
One capsule after the same meal
Take it about 30 minutes after the same meal every day, such as breakfast. This keeps tamsulosin levels steady and reduces dizziness.
Swallow it whole
Use a glass of water. Do not chew, crush or open the capsule, as the contents can irritate your mouth and throat.
Missed a dose?
Take it after your next meal that day. If a day has passed, skip it. Never take two capsules at once.
Stand up slowly for the first few days, especially at night, until you know how the capsule affects you. Do not take Duodart with another alpha blocker or with Avodart, as it already contains both medicines.
Is Duodart right for you?
Usually suitable for
Men with a diagnosed enlarged prostate and moderate to severe urinary symptoms
Men whose doctor wants both a quick effect and long-term shrinking
Men already taking dutasteride and tamsulosin separately who prefer one capsule
Not suitable, or check first
Women and children must not take Duodart
Allergy to dutasteride, tamsulosin, soya or peanut (the capsule contains soya lecithin)
Fainting or dizziness on standing, low blood pressure, or severe liver or kidney problems
Taking strong CYP3A4 blockers such as ketoconazole, or another alpha blocker
A high or rising PSA that has not been checked
PSA tests
Duodart roughly halves PSA after 6 months. Tell any doctor checking your PSA that you take it, and have a rising PSA looked into.
Eye surgery
Before cataract or glaucoma surgery, tell the eye doctor you take Duodart, as tamsulosin can affect the iris during the operation.
Leaking capsules and blood donation
Women who are or may be pregnant should avoid touching leaking capsules. Do not donate blood while on Duodart and for 6 months after the last dose.
Duodart side effects
Most men take Duodart without serious problems. Because it contains two medicines, side effects can come from either part: dizziness usually comes from tamsulosin, while sexual changes can come from both. Some ease with time; if any persist or bother you, tell your doctor.
More common
Less or no semen when you ejaculate, lower sex drive, difficulty getting an erection, and dizziness, especially when standing up.
Less common
Breast tenderness or enlargement, a blocked or runny nose, rash, and feeling tired or weak.
See a doctor promptly for
Fainting, a painful erection lasting more than 4 hours, swelling of the face, lips or throat, a severe rash, or a breast lump or nipple discharge.
Duodart price in Malaysia
One box of Duodart 0.5mg/0.4mg (30 capsules, one month) is RM299. Three boxes are RM867, saving RM30. The doctor review and delivery are included. Ordering takes three steps.
Step 1
Order Duodart
Choose 1 to 3 boxes and check out securely.
Step 2
Doctor review
A licensed doctor reads your health form and contacts you if anything needs clarifying.
Step 3
Delivered to you
Our pharmacy partner sends your capsules in plain, discreet packaging.
Free delivery across Malaysia Licensed pharmacy partner
Duodart 0.5mg/0.4mg product details
Active ingredients
Dutasteride 0.5mg and tamsulosin hydrochloride 0.4mg per capsule
Form
Hard capsule containing a dutasteride soft capsule and tamsulosin pellets
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Duodart FAQs, answered by doctors
Written by Dr. Brian Lopez and medically reviewed by Dr. Vijendran Krishnan.
Duodart is a capsule, not a tablet, although many people search for it as a Duodart tablet. Each oblong hard capsule holds a small soft capsule of dutasteride 0.5mg and tiny pellets of tamsulosin 0.4mg. Swallow it whole. Do not chew, crush or open it, because dutasteride can irritate the mouth and throat.
Duodart is used for moderate to severe urinary symptoms caused by benign prostatic hyperplasia (BPH), an enlarged prostate that is not cancer. It also lowers the risk of acute urinary retention, when you suddenly cannot pass urine, and of needing prostate surgery. It is not a treatment for prostate cancer, erection problems or hair loss.
You may notice an easier flow within the first one to two weeks, thanks to the tamsulosin part. The dutasteride part shrinks the prostate slowly, so the full effect builds over 3 to 6 months. Doctors usually review how well it is working at around 6 months, so keep taking it daily even if early changes are small.
Not together. Duodart already contains both dutasteride and tamsulosin, so taking it with tamsulosin, Avodart or another alpha blocker would double the dose. If your doctor switches you to Duodart, it replaces those medicines. Always tell the doctor about everything you take, including blood pressure tablets.
Take one capsule about 30 minutes after the same meal each day, for example after breakfast. Food slows how fast tamsulosin is absorbed, which lowers the chance of feeling dizzy or light headed, especially in the first few days. Keeping to the same meal also makes the effect steadier.
Yes. After about 6 months, the dutasteride in Duodart lowers PSA readings by about half. Doctors adjust for this when reading your result. Tell anyone who checks your PSA that you take Duodart, and have any rise in PSA while on it checked, as it can still be a sign of prostate cancer.
Yes. Tamsulosin can cause floppy iris syndrome, which makes eye surgery harder for the surgeon. Tell your eye doctor that you take Duodart before any cataract or glaucoma operation. Do not stop it on your own; the eye team will advise you.
If you remember on the same day, take it after your next meal. If it is already the next day, skip the missed capsule and carry on as normal. Never take two capsules at once. If you miss several days in a row, ask your doctor before restarting, as the tamsulosin part may make you dizzy again at first.
The tamsulosin effect wears off within days, so your flow may weaken quickly. The prostate then slowly grows back over the following months. Duodart controls an enlarged prostate rather than curing it, so most men take it long term. Speak to your doctor before stopping.
Duodart 0.5mg/0.4mg is RM299 for 30 capsules at Hello Doktor, about one month. Three boxes are RM867, saving RM30. It is a prescription medicine, so a licensed Malaysian doctor reviews your health form before our licensed pharmacy partner sends it in discreet packaging, with free delivery across Malaysia.
This page is for education and does not replace a consultation. Duodart is a prescription medicine for men with an enlarged prostate. Urinary symptoms can also come from infection, bladder problems or prostate cancer, so have them assessed by a doctor.