Insulin and glucagon are two hormones that play a major role in regulating the blood glucose level; therefore, they are directly related to serious health conditions such diabetes, hypoglycemia, or some other sugar problem.
What are Insulin and Glucagon?
Insulin and glucagon are both produced by the islet cells of the pancreas and emitted in response to the blood sugar levels but contradict each other. Insulin will be released according to the signal of high blood glucose. Since insulin influences a few cells like muscle, red blood cells, and fat cells; these cells will absorb the glucose out of the blood in order to decrease the level of sugar in the blood. Once, these cells are out of storage, the glucose will be delivered to the fat cells. Contrarily, glucagon is secreted when the blood glucose and it can also affect many cells of the body, but particularly the liver. As a result, glucagon will burn up fat to make energy for the body. Insulin and glucagon work in harmony to remain the optimal amount of blood glucose in our body.
What are the risks of Insulin and Glucagon?
Insulin resistance is the root of many types of disease, noticeably type 2 diabetes and prediabetes. This is a condition when the muscle, fat, and liver cells cannot sense properly the signal of insulin and are unable to take in the glucose in the bloodstream. The body, consequently, will need a higher intake of glucose for absorption. Insulin produced by the beta cells in the pancreas will increase dramatically to fulfill the body’s need or else the extra glucose will accumulate in the bloodstream, which gives rise to diabetes, prediabetes, and other serious health disorders. Even though the research behind insulin resistance causes is not backed up satisfyingly, overweightedness and physical inactivity are believed to be the main factors.
Importance of fat loss
Contrary to insulin resistance is insulin sensitivity since the body can avoid the excessive amount of glucose entering the body. This process is one of the keys to fat loss. Once the body is sensitive to insulin, it will produce less insulin than necessary. The greater the insulin circulation is in our blood, the more likely we experience high blood pressure, heart disease and heart failure, obesity, osteoporosis and even cancer. However, we can still face problem due to a high level of insulin sensitivity such as hypoglycemia.
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Review Date: January 4, 2017 | Last Modified: January 4, 2017
Normal Regulation of Blood Glucose. http://www.endocrineweb.com/conditions/diabetes/normal-regulation-blood-glucose. Accessed August 22, 2016.
Prediabetes and Insulin Resistance. https://www.niddk.nih.gov/health-information/diabetes/types/prediabetes-insulin-resistance. Accessed August 22, 2016.
Insulin Sensitivity. http://www.diabetes.co.uk/insulin/insulin-sensitivity.html. Accessed August 22, 2016.