The circulatory system and the kidneys support each other to maintain good health. The kidneys need a number of blood vessels to filter wastes and excess fluids from blood. When the blood vessels are damaged, oxygen and nutrients cannot reach nephrons which have the function to filter your blood, so nephrons cannot work well. High blood pressure (hypertension) is, as a result, the leading cause of kidney disease and kidney failure (end-stage renal disease).
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