In 1830, Rokushu Yamamoto described a peculiar condition of a 45 year old man in his private practice record. The said man initially came to Yamamoto with a complain of high grade fever and a year later, while examining the man, Yamamoto found that there were no palpable pulses on the patient’s upper limbs and carotid. Later on, the patient lost weight, had difficulty in breathing and the aforementioned problems worsened with time before he eventually died many years after.
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