Causes of Type 2 Diabetes


Type 2 diabetes is the most common form of diabetes. It usually occurs when body’s cells cannot use insulin properly and effectively. This leads to high blood sugar levels if diabetes is untreated. Knowing what triggers this diabetes type may help in managing your condition. Causes of type 2 diabetes are shown below.

Insulin resistance

Insulin is a hormone that controls blood sugar levels. It is produced by beta cells in the pancreas. When the level of sugar in your blood is higher than normal, the excessive sugar will be stored in the body for later use.
When liver, muscles and fat cells do not use insulin properly, the blood sugar level rises. The body cannot use glucose for energy and this can lead to the symptoms of type 2 diabetes.

Abnormal glucose production by the liver

In some people, livers produce more glucose than the body’s need, this contributes to high blood sugar levels. The pancreas produces insulin for the liver to store glucose for later use and glucagon when blood sugar levels are low. With glucagon livers turn glycogen into glucose and release it to the blood stream. However, due to some unknown reasons, the levels of glucagon stay higher than normal, causing the liver to keep producing glucose, which leads to high blood sugar levels. This can also contribute to the symptoms of type 2 diabetes.

Cell signaling and regulation

Cells communicate with others through a complicated network. In a normal state, they receive signals to release a hormone that controls blood sugar levels. Problems in cell signaling systems can destroy the signal chain and stop the communication, causing problems in managing blood sugar. These problems result in high blood sugar levels which is among the symptoms of type 2 diabetes.

Beta cell dysfunction

Studies have shown that beta cell dysfunction contributes to type 2 diabetes. Because insulin is produced by beta cells in the pancreas, the dysfunction of these cells can lead to abnormal insulin release. When insulin is not released normally, the blood sugar control function is affected. Also, as a cycle, the beta cells can be damaged by the high levels of blood sugar.
Type 2 diabetes may be the result of a number of causes and they are very different from one another. Some causes are common, some are rare. However, the general way to prevent this disease is to build a healthy lifestyle.
Hello Health Group does not provide medical advice, diagnose or treatment.

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