By Medically reviewed by hellodoktor

Generic Name: Nyolol Brand Name(s): Generics only. No brands available.


What is Nyolol® eye drop used for?

Nyolol® eye drop is commonly used for ocular hypertension, chronic open-angle glaucoma, and aphakic glaucoma.

How should I take Nyolol® eye drop?

Before putting in your eye drops, you need to wash your hand and make sure not to let the tip of the dropper touch any surface.

Firstly, tilt your head back, pull down the lower lid of your eye with your index finger to form a pocket. Hold the dropper (tip down) with the other hand, as close to the eye as possible without touching it. While looking up, gently squeeze the dropper so that a single drop falls into the pocket made by the lower eyelid. Remove your index finger from the lower eyelid. Close your eye for 2 to 3 minutes and tip your head down as though looking at the floor. Try not to blink or squeeze your eyelids. Place a finger on the tear duct and apply gentle pressure. Wipe any excess liquid from your face with a tissue.

How do I store Nyolol® eye drop?

Nyolol® eye drop is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Nyolol® eye drop in the bathroom or the freezer. There may be different brands of Nyolol® eye drop that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Nyolol® eye drop down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Nyolol® eye drop?

Sportsmen should take care that this special contains an active product which can induce in a positive way the tests made during anti-doping controls.

As with other topically applied ophthalmic drugs; this drug may be absorbed systemically and lead to systemic effects of beta-blockers.

Cardiac insufficiency should be adequately controlled before starting therapy with Nyolol® eye drop. In patients with a history of severe cardiac disease and in elderly patients, signs of cardiac insufficiency should be watched for and pulse rates should be checked.

Although Nyolol® eye drop is well tolerated in glaucomatous patients wearing contact lenses as well as in aphakic patients, the wearing of contact lenses should be avoided due to the risk of:

  • Decrease of lacrimal secretion due to beta-blockers
  • Absorption on the lens of some components of the drug
  • Keratitis while wearing soft contact lenses due to symptoms

Nyolol® eye drop is not recommended in premature baby and newborn.

If the pack is unopened, Nyolol® eye drop can be used until the expiry date indicated with “EXP” on the pack. When you first open the bottle, screw on strongly the perforating cap to pierce the top of the bottle. After use, systematically screw on strongly the cap and put the bottle back in as box away from light. To be used within 30 days after first opening.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Nyolol® eye drop during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Nyolol® eye drop.

Side effects

What side effects can occur from Nyolol® eye drop?

Some side effects may occur when using this eye drop, including:

  • Symptoms of ocular irritation, including conjunctivitis, blepharitis, keratitis, corneal hypoesthesis, visual disturbances including refractive changes (due to withdrawal of miotics therapy in some cases), diplopia and ptosis
  • Cardiovascular such as bradycardia, arrhythmia, hypotension, syncope, heart block, cerebrovascular accident, cerebral ischemia, congestive heart failure, palpitation, cardiac arrest
  • Respiratory including bronchospasm (predominantly in patients with pre-existing bronchospastic disease), respiratory failure, dyspnea
  • Systemic including headache, asthenia, nausea, dizziness, depression, fatigue
  • Hypersensitivity reactions, including localized and generalized rash and urticaria


What drugs may interact with Nyolol® eye drop?

Nyolol® eye drop may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Especially if you are taking:

  • Those of beta-adrenergic blocking agents such as calcium channel blockers, catecholamine-depleting drugs, because beta-adrenergic blocking agents may lead to hypotension and/or severe bradycardia, and when combined with Nyolol® eye drop may produce additive effects.

Does food or alcohol interact with Nyolol® eye drop?

Nyolol® eye drop may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Nyolol® eye drop?

Nyolol® eye drop may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Bronchial asthma
  • Bronchospasm
  • History of bronchial asthma or severe chronic obstructive pulmonary disease
  • Uncontrolled congestive cardiac insufficiency
  • Cardiogenic shock
  • High atrioventricular block (without apparatus)
  • Raynaud’s phenomena
  • High bradycardia (pulse rates)


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Nyolol® eye drop.

What is the dose of Nyolol® eye drop for an adult?

The usual starting dose is one drop of 0.25% Nyolol® eye drop in the affected eye twice a day. If the clinical response is not adequate, the dosage may be changed to one drop of 0.50% solution in the affected eye twice a day. If necessary the physician may institute a concomitant therapy:

  • Either a sympathomimetic or para-sympathomimetic antiglaucoma ophthalmic solution
  • Or systemically administered carbonic anhydrase inhibitors, in order to obtain a better response

Since in some patients the pressure-lowering response to Nyolol® eye drop may require a few weeks to stabilize, evaluation should include a determination of intraocular pressure after approximately 4 weeks of treatment with Nyolol® eye drop. If the intraocular pressure is maintained at satisfactory levels, the dosage schedule may be changed to one drop once a day.

What is the dose of Nyolol® eye drop for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Nyolol® eye drop available?

Nyolol® eye drop is available in the following dosage forms and strengths:

  • Nyolol® eye drop 5ml contains Timolol Maleate 6.8 mg (equiv. to Timolol base 5 mg or 0.5%).

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Nyolol® eye drop, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.