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Natrilix® is commonly used for treating high blood pressure alone or along with other medicines. It is also used to treat salt and water retention (swelling) associated with congestive heart failure.
Use indapamide as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use indapamide.
Natrilix® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Natrilix® in the bathroom or the freezer. There may be different brands of Natrilix® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush Natrilix® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Do not use indapamide if:
Contact your doctor or health care provider right away if any of these apply to you.
Important safety information is:
Pregnancy
If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using indapamide while you are pregnant.
Breastfeeding:
It is not known if this medicine is found in breast milk. Do not breastfeed while taking indapamide.
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome:
Seek medical attention right away if any of these severe side effects occur:
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects.
Natrilix® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Some medicines may interact with indapamide are:
Natrilix® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
Natrilix® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.
These health conditions are:
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Natrilix® (indapamide).
Hypertension:
The adult starting dose is 1.25 mg as a single daily dose taken in the morning. If the response to 1.25 mg is not satisfactory after four weeks, the daily dose may be increased to 2.5 mg taken once daily. If the response to 2.5 mg is not satisfactory after four weeks, the daily dose may be increased to 5 mg taken once daily, but adding another antihypertensive should be considered.
Edema of congestive heart failure:
The adult starting dose for edema of congestive heart failure is 2.5 mg as a single daily dose taken in the morning. If the response to 2.5 mg is not satisfactory after one week, the daily dose may be increased to 5 mg taken once daily.
If the antihypertensive response is insufficient, indapamide may be combined with other antihypertensive drugs, with careful monitoring of blood pressure. It is recommended that the usual dose of other agents be reduced by 50% during initial combination therapy. As the blood pressure response becomes evident, further dosage adjustments may be necessary.
In general, doses of 5 mg and larger have not appeared to provide additional effects on blood pressure or heart failure, but are associated with a greater degree of hypokalemia. There is minimal clinical trial experience in patients with doses greater than 5 mg once a day.
The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.
Natrilix® is available in the following dosage forms and strengths:
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
If you miss a dose of Natrilix®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
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