Vaxem Hib


Generic Name: Vaxem Hib Brand Name(s): Generics only. No brands available.


What is Vaxem Hib (Haemophilus influenza type B) used for?

Vaxem Hib is commonly used for active immunization against invasive disease caused by Haemophilus influenzae type b in children from 2 months of age.

Vaxem Hib does not stimulate protection against diseases caused by different Haemophilus influenzae serotypes and from other meningitis types, which are caused by different pathogen agents.

How should I take Vaxem Hib (Haemophilus influenza type B)?

Vaxem Hib should be administered intramuscularly in the anterolateral area of the thigh in infants. Do not administer intravascularly.

The vaccine should be shaken before use.

How do I store Vaxem Hib (Haemophilus influenza type B)?

Vaxem Hib is best stored in the refrigerator. To prevent drug damage, do not freeze. There may be different brands of Vaxem Hib that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Vaxem Hib down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Vaxem Hib (Haemophilus influenza type B)?

Vaxem Hib is contraindicated in case of:

  • Hypersensitivity to the vaccine components or a severe reaction to a previous dose. Vaxem Hib will not harm individuals previously infected with the Hib bacteria.
  • As with other vaccines, vaccination should be postponed in subjects suffering from acute severe febrile illness. The presence of a minor nonfebrile infection, however, is not a contraindication to vaccination.

Also, there is some important information that you may notice:

  • According to WHO recommendations, children infected with human immunodeficiency virus (HIV) both asymptomatic and symptomatic, should be immunized with Vaxem Hib vaccine according to standard schedules.
  • As with all vaccinations, appropriate medical treatment should be available for injection should an anaphylactic reaction occur. Recipients of the vaccine should remain under observation, until they have been seen to be in good health and not to be experiencing an immediate adverse reaction.
  • Vaxem Hib should be administered with caution to subjects with thrombocytopenia or a bleeding disorder since bleeding may occur following an intramuscular administration to these subjects. In these subjects the vaccine may be administered by deep subcutaneous injection.
  • Do not administer intravenously. Care should be taken that the needle of the syringe does not penetrate the lumen of a blood vessel.
  • In the presence of congenital or acquired immune deficiency, Vaxem Hib may be administered but a protective immune response may not be elicited.
  • Although a limited immune response to the diphtheria toxin component
    may occur, vaccination with Vaxem Hib does not substitute for routine diphtheria vaccination.
  • Vaxem Hib does not elicit protection against diseases caused by other influenzae serotypes and does not protect against meningitis caused by other pathogenic agents.
  • Vaxem Hib should under no circumstances be administered intravascularly.

Consult doctor if your child have experienced adverse reactions after the
administration of the vaccine, or if your child suffer from any kind of

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using this medication during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication.

Side effects

What side effects can occur from Vaxem Hib (Haemophilus influenza type B)?

The administration of any kind of vaccine may cause hypersensitivity reactions, rarely including the anaphylactic reaction, whose characteristic symptoms are:

  • Serious and immediate hypotension
  • Accelerated or retarded heartbeat
  • Tiredness
  • Unusual weakness
  • Anxiety
  • Restlessness
  • Loss of consciousness
  • Difficulty in breathing and deglutition
  • Itching (especially at the sole of the foot and at the palm of the hands)
  • Urticarial with or without angioedema (swollen and hitching skin areas localized more frequently at the extremities, at the external genitals and at the face, mainly at the eye and lips regions)
  • Erythema (especially around the ears)
  • Nausea
  • Vomit
  • Abdominal pain
  • Diarrhea

Besides, these common side effects may occur:

  • Tenderness
  • Erythema
  • Induration
  • Unusual crying
  • Irritability
  • Vomiting
  • Diarrhea
  • Change in eating habits
  • Sleepiness
  • Fever
  • Rash
  • Agitation
  • Unusual crying

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Vaxem Hib (Haemophilus influenza type B)?

Vaxem Hib may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Vaxem Hib (Haemophilus influenza type B)?

Vaxem Hib may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Vaxem Hib (Haemophilus influenza type B)?

Vaxem Hib may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Vaxem Hib (Haemophilus influenza type B).

What is the dose of Vaxem Hib (Haemophilus influenza type B) for an adult?

The dosage has not been established in adults.

What is the dose of Vaxem Hib (Haemophilus influenza type B) for a child?

Under 13 months of age:

Three 0.5ml doses, with an interval of at least four weeks between doses, the first dose is given not earlier than two months of age.

13 months of age and over:

The recommended dose is single 0.5ml dose.

Vaxem Hib is not recommended for healthy children aged more than four years.

How is Vaxem Hib (Haemophilus influenza type B) available?

Vaxem Hib is available in the following dosage forms and strengths:

  • Each single dose of 0.5 ml dose contains: 10 µg of capsular oligosaccharide of H. influenzae type b conjugated to approx. 25 µg of CRM 197 protein

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

This vaccine has been administered by your doctor through standard schedule.

Hello Health Group does not provide medical advice, diagnosis or treatment.


Review Date: March 12, 2017 | Last Modified: March 12, 2017

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