By Medically reviewed by hellodoktor

Generic Name: Vasobral Brand Name(s): Vasobral.


What is Vasobral® (Caffeine, Dihydroergocryptine Mesylate) used for?

Vasobral® is commonly used for management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.

Vasobral® is often combined with analgesics or with ergot alkaloids to treat migraine and other headache types. Over the counter, Vasobral® is available to treat drowsiness or mild water-weight gain.

How should I take Vasobral® (Caffeine, Dihydroergocryptine Mesylate)?

Take Vasobral® inside meals (during meals, with a little water).

How do I store Vasobral® (Caffeine, Dihydroergocryptine Mesylate)?

Vasobral® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Vasobral® in the bathroom or the freezer. There may be different brands of Vasobral® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Vasobral® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Vasobral® (Caffeine, Dihydroergocryptine Mesylate)?

Before using this drug, tell your doctor if you have:

  • Hypersensitivity to any ingredients of Vasobral®
  • Glaucoma

Using this drug during pregnancy may lead to a decrease in the lactation. Caffeine contained in the product can cause a sleep disorder, tachycardia.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Vasobral® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Vasobral®.

Side effects

What side effects can occur from Vasobral® (Caffeine, Dihydroergocryptine Mesylate)?

Some side effects may occur when using this drug, including:

Side effects typically occur during the first days of therapy and are usually transient. In this case, stop treatment and consult your doctor.

In the case of L-dopa treatment, side effects such as stomach pain, heartburn, hypotension and headache are increased and are also reported the occurrence of edema.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Vasobral® (Caffeine, Dihydroergocryptine Mesylate)?

Vasobral® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Vasobral® (Caffeine, Dihydroergocryptine Mesylate)?

Vasobral® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Vasobral® (Caffeine, Dihydroergocryptine Mesylate)?

Vasobral® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Vasobral® (Caffeine, Dihydroergocryptine Mesylate).

What is the dose of Vasobral® (Caffeine, Dihydroergocryptine Mesylate) for an adult?

The recommended dose is 1–2 tablets or 2–4 ml (1–2 pipette), 2 times a day.

What is the dose of Vasobral® (Caffeine, Dihydroergocryptine Mesylate) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Vasobral® (Caffeine, Dihydroergocryptine Mesylate) available?

Vasobral® is available in the following dosage forms and strengths:

  • Tablet; Oral; Caffeine 40 mg; Dihydroergocryptine Mesylate 4 mg
  • Solution; Oral; Caffeine 10 mg; Dihydroergocryptine Mesylate 1 mg / ml

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Vasobral®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.


Review Date: March 8, 2017 | Last Modified: September 13, 2019

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