Know the basics
What is Urea used for?
Urea is used to treat dry/rough skin conditions (e.g., eczema, psoriasis, corns, callus) and some nail problems (e.g., ingrown nails). It may also be used to help remove dead tissue in some wounds to help wound healing. Urea is known as a keratolytic. It increases moisture in the skin by softening/dissolving the horny substance (keratin) holding the top layer of skin cells together. This effect helps the dead skin cells fall off and helps the skin keep more water in.
How should I take Urea?
Use this product as directed. Follow all directions on the product package and prescription label. If you are uncertain about any of the information, consult your doctor or pharmacist.
Some products need to be shaken well before use. Check the label to see whether you should shake the bottle. Apply to the affected areas of the skin/nails, usually 1 to 3 times a day or as directed by your doctor. Rub in well until absorbed. Wash your hands after applying unless you are treating the hands. How often you apply the medication will depend on the product and your skin condition.
Apply to the skin/nails only. Avoid sensitive areas such as your eyes, lips, inside your mouth/nose, and the vaginal/groin area, unless your doctor directs you otherwise. Ask your doctor or check the label for directions about any areas or types of skin where you should not apply the product (e.g., the face, broken/chapped/cut/irritated/scraped skin, or recently shaved skin). Ask your doctor if you should cover the treated area with a bandage or gauze. Consult your doctor or pharmacist for more details.
Use this medication regularly to get the most benefit from it.
Tell your doctor if your condition persists or worsens.
How do I store Urea?
Urea is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store urea in the bathroom or the freezer. There may be different brands of urea that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush urea down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Know the precautions & warnings
What should I know before using Urea?
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Although there is no specific information comparing use of urea in teenagers with use in other age groups, this medicine is not expected to cause different side effects or problems in teenagers than it does in adults.
Is it safe to take Urea during pregnancy or breast-feeding?
There isn’t enough information about the safety of using this medication during pregnancy and breast-feeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication.
Know the side effects
What are the side effects of Urea?
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
- irregular heartbeat
- muscle cramps or pain
- numbness, tingling, pain, or weakness in hands or feet
- unusual tiredness or weakness
- weakness and heaviness of legs
Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.
Know the interactions
What drugs may interact with Urea?
Urea may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Arsenic Trioxide
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Does food or alcohol interact with Urea?
Urea may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
What health conditions may interact with Urea?
Urea may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, especially:
- Diabetes mellitus (sugar diabetes)
- Fibroid tumors of the uterus
- Kidney disease
- Liver disease
- Sickle cell disease
Understand the dosage
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.
What is the dose of urea for an adult?
Urea 30% foam:
Urea 35% foam:
Urea 35% lotion:
Urea 39% cream:
Urea 40% foam:
Urea 42% foam:
Urea 45% emulsion:
Urea 45% solution:
Urea 50% emulsion:
Urea 50% ointment:
Urea 50% suspension:
Apply to affected skin twice/day.
Urea 40% emulsion:
Urea 40% suspension:
Urea 42% pad:
Urea 45% gel:
Urea 50% cream:
Urea 50% gel:
Apply to nail tissue or affected skin twice/day.
Urea 50% stick:
Apply to affected nail tissue twice/day.
What is the dose of urea for a child?
The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.
How is urea available?
Urea is available in the following dosage forms and strengths:
- Powder for solution
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of urea, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Urea. https://www.drugs.com/cdi/urea-cream.html. Accessed July 15, 2016.
Urea. http://www.healthline.com/drugs/urea/topical-cream#Highlights1. Accessed July 15, 2016.
Urea. http://www.webmd.com/drugs/2/drug-6047-164/urea-topical/emollients-topical/details. Accessed July 15, 2016.
Review Date: May 8, 2017 | Last Modified: May 8, 2017