Generic Name: Triprolidine Brand Name(s): Generics only. No brands available.

Know the basics

What is triprolidine used for?

Triprolidine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, watery eyes, itchy eyes/nose/throat/skin, cough, runny nose, and sneezing.

This medication works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. By blocking another natural substance made by your body (acetylcholine), it helps dry up some body fluids to relieve symptoms such as watery eyes and runny nose.

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.

These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

How should I take triprolidine?

Take this medication by mouth with or without food as directed by your doctor, usually every 6 hours. Do not take more than 4 doses in a 24-hour period. Follow all directions on the product package. This medication may be taken with food or milk if stomach upset occurs.

Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

The dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this medication more often than directed. Do not take more of this medication than recommended for your age. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

If your symptoms do not improve after 7 days, if they worsen, if you develop fever/chills, or if you think you may have a serious medical problem, get medical help right away.

How do I store triprolidine?

Triprolidine is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store triprolidine in the bathroom or the freezer. There may be different brands of triprolidine that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush triprolidine down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Know the precautions & warnings

What should I know before using triprolidine?

Some medical conditions may interact with triprolidine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a fast, slow, or irregular heartbeat

Is it safe to take triprolidine during pregnancy or breast-feeding?

There isn’t enough information about the safety of using this medication during pregnancy and breast-feeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication.

Know the side effects

What are the side effects of triprolidine?

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: dizziness; drowsiness; dry mouth, nose, or throat; excitability; nervousness or anxiety; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, light-headedness, or headache; tremor.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Know the interactions

What drugs may interact with triprolidine?

Triprolidine may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Some MEDICINES MAY INTERACT with triprolidine. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Sodium oxybate (GHB) because it may increase the risk of triprolidine’s side effects

Does food or alcohol interact with triprolidine?

Triprolidine may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with triprolidine?

Triprolidine may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, especially a history of asthma or other lung or breathing problems (eg, emphysema, chronic bronchitis), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, a blockage of your stomach or bowels, ulcers, a blockage of your bladder, trouble urinating, an enlarged prostate, seizures, or an overactive thyroid.

Understand the dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.

What is the dose of triprolidine for an adult?

Zymine

Adults and Children (12 yr of age and older)

PO 2.5 mg every 4 to 6 h (max, 10 mg per 24 h).

Zymine XR

Adults and Children (12 yr of age and older)

PO 5 mg every 12 h (max, 10 mg per 24 h).

What is the dose of triprolidine for a child?

Zymine

Children (6 to 12 yr of age)

PO 1.25 mg every 4 to 6 h (max, 5 mg per 24 h).

Children (4 to 6 yr of age)

PO 0.94 mg every 4 to 6 h (max, 3.75 mg per 24 h).

Children (2 to 4 yr of age)

PO 0.625 mg every 4 to 6 h (max, 2.5 mg per 24 h).

Children (4 mo to 2 yr of age)

PO 0.31 mg every 4 to 6 h (max, 1.25 mg per 24 h).

Zymine XR

Children (6 to 12 yr of age)

PO 2.5 mg every 12 h (max, 5 mg per 24 h).

Children (2 to 6 yr of age)

PO 1.25 mg every 12 h (max, 2.5 mg per 24 h).

How is triprolidine available?

Triprolidine is available in the following dosage forms and strengths:

Liquid 1,25 mg/5 mL

Suspension 2,5 mg/5 mL

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of triprolidine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: January 4, 2017 | Last Modified: January 4, 2017

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