Generic Name: Trileptal Brand Name(s): Generics only. No brands available.


What is Trileptal® (oxcarbazepine) used for?

Trileptal® is commonly used for decreasing nerve impulses that cause seizures.

It is used as a single medicine in adults and children who are at least 4 years old, and with other medicines in adults and children who are at least 2 years old.

How should I take Trileptal® (oxcarbazepine)?

  • Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
  • Give the liquid directly from the oral syringe, or mix the medicine with a small glass of water. After using the syringe, rinse it with water and allow it to air dry.
  • You may take the Trileptal® oral liquid or tablet with or without food.
  • Do not stop using Trileptal® suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Get your prescription refilled before you run out of medicine completely.
  • While using Trileptal®, you may need frequent blood tests.
  • Wear a medical alert tag or carry an ID card stating that you take Trileptal®. Any medical care provider who treats you should know that you are using oxcarbazepine.
  • Seizures are often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor’s advice.

How do I store Trileptal® (oxcarbazepine)?

Trileptal® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Trileptal® in the bathroom or the freezer. There may be different brands of Trileptal® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Trileptal® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Trileptal® (oxcarbazepine)?

To make sure Trileptal® is safe for you, tell your doctor if you:

  • Have liver disease.
  • Have kidney disease.
  • Have depression, or a mood disorder.
  • Have a history of suicidal thoughts or actions.
  • Are allergic to oxcarbazepine.
  • Are allergic to carbamazepine (Carbatrol, Tegretol).

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using Trileptal®. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Is it safe during pregnancy or breastfeeding?


Do not start or stop taking Trileptal® during pregnancy without your doctor’s advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant while taking Trileptal® for seizures.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of Trileptal® on the baby.

Oxcarbazepine can make birth control pills less effective. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy while taking oxcarbazepine.


Oxcarbazepine can pass into breast milk and may harm a nursing baby. You should not breastfeed while you are taking Trileptal®.

Side effects

What side effects can occur from Trileptal® (oxcarbazepine)?

Get emergency medical help if you have any signs of an allergic reaction to Trileptal®:

  • Hives
  • Difficult breathing
  • Swelling of your face, lips, tongue, or throat

Trileptal® can reduce the sodium in your body to dangerously low levels, which can cause a life-threatening electrolyte imbalance.

Call your doctor right away if you have:

  • Headache
  • Problems with thinking or memory
  • Weakness
  • Loss of appetite
  • Feeling unsteady
  • Confusion
  • Hallucinations
  • Fainting
  • Shallow breathing
  • Severe seizures

 Also call your doctor at once if you have:

  • Increased seizures (or more severe seizures)
  • Sores around your eyes
  • Painful mouth sores
  • Trouble swallowing
  • Problems with speech, balance, or walking
  • Liver problems – nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
  • Signs of inflammation in your body – swollen glands, flu symptoms, easy bruising or bleeding, severe tingling or numbness, muscle weakness, upper stomach pain, jaundice (yellowing of the skin or eyes), chest pain, new or worsening cough with fever, trouble breathing
  • Severe skin reaction – fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling

Common side effects may include:

  • Dizziness, drowsiness, tired feeling
  • Headache
  • Weakness
  • Balance problem
  • Nausea, vomiting, stomach pain, indigestion
  • Tremors or shaking
  • Vision problems, double vision
  • Fever, chills, cold or flu symptoms (in children)

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.


What drugs may interact with Trileptal® (oxcarbazepine)?

Trileptal® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Trileptal® (oxcarbazepine)?

Trileptal® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Trileptal® (oxcarbazepine)?

Trileptal® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Trileptal® (oxcarbazepine).

What is the dose of Trileptal® (oxcarbazepine) for an adult?

Adjunctive therapy for adults

Initially: a dose of 600 mg/day, twice a day.

If clinically indicated, the dose may be increased by a maximum of 600 mg/day at approximately weekly intervals.

The recommended daily dose is 1200 mg/day.

Patients with hepatic impairment

In general, dose adjustments are not required in patients with mild-to-moderate hepatic impairment.

Patients with renal impairment

In patients with impaired renal function, Trileptal® therapy should be initiated at one-half the usual starting dose (300 mg/day) and increased slowly to achieve the desired clinical response.

What is the dose of Trileptal® (oxcarbazepine) for a child?

Adjunctive therapy for pediatric patients (aged 2-16 years)

In pediatric patients aged 4-16 years, a daily dose is 8-10 mg/kg generally not to exceed 600 mg/day, given in a twice-a-day regimen.

In pediatric patients aged 2 – < 4 years, a daily dose is 8-10 mg/kg generally not to exceed 600 mg/day, given in a twice-a-day regimen.

For patients under 20 kg, a starting dose of 16-20 mg/kg may be considered. The maximum maintenance dose of Trileptal® should be achieved over 2-4 weeks and should not exceed 60 mg/kg/day in a twice-a-day regimen.

How is Trileptal® (oxcarbazepine) available?

Trileptal® is available in the following dosage forms and strengths:

  • Trileptal® tablet 150mg
  • Trileptal® tablet 600mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Trileptal®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.



Review Date: January 4, 2017 | Last Modified: January 4, 2017

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