What is Toradol® (ketorolac) used for?
Toradol® is a nonsteroidal anti-inflammatory drug (NSAID). Ketorolac works by reducing hormones that cause inflammation and pain in the body.
Toradol® is used short-term (5 days or less) to treat moderate to severe pain.
Toradol® may also be used for purposes not listed in this medication guide.
How should I take Toradol® (ketorolac)?
Toradol® is usually given first as an injection, and then as an oral (by mouth) medicine. The injection is given into a muscle, or into a vein through an IV. A healthcare provider will give you the injection.
Follow all directions on your prescription label. Do not take this medicine in larger amounts or for longer than recommended. Use the lowest dose that is effective in treating your condition.
Toradol® should not be used for longer than 5 days, including both injection plus tablets. Long-term use of this medicine can damage your kidneys or cause bleeding.
How do I store Toradol® (ketorolac)?
Toradol® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Toradol® in the bathroom or the freezer. There may be different brands of Toradol® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush Toradol® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Precautions & warnings
What should I know before using Toradol® (ketorolac)?
Before using this drug, tell your doctor if:
- You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
- You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
- You have allergy with any of active or inactive ingredients of Toradol® or other medications.
- You have any other illnesses, disorders, or medical conditions.
Toradol® can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Even people without heart disease or risk factors could have a stroke or heart attack while taking this medicine.
Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).
Toradol® may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using Toradol®, especially in older adults.
You should not use Toradol® if you have:
- Active or recent stomach ulcer, stomach bleeding, or intestinal bleeding
- A bleeding or blood-clotting disorder
- A closed head injury or bleeding in your brain
- Bleeding from a recent surgery
- Severe kidney disease or dehydration
- A history of asthma or severe allergic reaction after taking aspirin or an NSAID
- If you are scheduled to have surgery (especially bypass surgery)
- If you are in late pregnancy or you are breastfeeding a baby
Is it safe during pregnancy or breastfeeding?
There are no adequate studies in women for determining risk when using Toradol® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Toradol®. Toradol® is pregnancy risk category C, according to the US Food and Drug Administration (FDA).
FDA pregnancy risk category reference below:
- A=No risk
- B=No risk in some studies
- C=There may be some risk
- D=Positive evidence of risk
What side effects can occur from Toradol® (ketorolac)?
Common side effects may include:
- Stomach pain
Stop using Toradol® and call your doctor at once if you have:
- Shortness of breath (even with mild exertion)
- Swelling or rapid weight gain
- The first sign of any skin rash, no matter how mild
- Signs of stomach bleeding – bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds
- Liver problems – nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
- Kidney problems – little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath
- Low red blood cells (anemia) – pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating
- Severe skin reaction – fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling
Get emergency medical help if you have signs of an allergic reaction to Toradol®: sneezing, runny or stuffy nose; wheezing or trouble breathing; hives; swelling of your face, lips, tongue, or throat.
Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath.
Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.
What drugs may interact with Toradol® (ketorolac)?
Toradol® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Products that may interact with this drug are:
- Heparin or warfarin (Coumadin, Jantoven)
- Antipsychotic medicine
- Heart or blood pressure medication, including a diuretic or “water pill”
- Seizure medicine (carbamazepine, phenytoin)
- Steroid medicine (such as prednisone)
Does food or alcohol interact with Toradol® (ketorolac)?
Toradol® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
What health conditions may interact with Toradol® (ketorolac)?
Toradol® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.
Health conditions that may interact with this drug are:
- Heart disease
- High blood pressure
- High cholesterol
- A history of heart attack, stroke, or blood clot
- A history of stomach ulcers or bleeding
- Inflammatory bowel disease, ulcerative colitis, or Crohn’s disease
- Liver disease
- Kidney disease (or if you are on dialysis)
- Fluid retention
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Toradol® (ketorolac).
What is the dose of Toradol® (ketorolac) for an adult?
Patients age 17 to 64: 20 mg PO once followed by 10 mg q4-6hours prn not >40 mg/day.
Patients age ≥65, renally impaired, and/or weight<50 kg (110 lbs): 10 mg PO once followed by 10 mg q4-6 hours prn not >40 mg/day.
What is the dose of Toradol® (ketorolac) for a child?
The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.
How is Toradol® (ketorolac) available?
Toradol® is available in the following dosage forms and strengths:
- Tablet, film coated ketorolac tromethamine 10mg
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of Toradol®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Toradol®. http://www.webmd.com/drugs/2/drug-6418/toradol-injection/details. Accessed July 14, 2017
Toradol®. https://www.drugs.com/dosage/toradol.html. Accessed July 14, 2017
Review Date: July 14, 2017 | Last Modified: September 13, 2019