Tobramicina IBI

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Generic Name: Tobramicina IBI Brand Name(s): Generics only. No brands available.

Uses

What is tobramicina IBI (tobramicina solfato) used for?

Tobramicina IBI is commonly used for treating serious infections caused by certain bacteria.

How should I take tobramicina IBI (tobramicina solfato)?

Tobramicina IBI is usually given as an injection at your doctor’s office, hospital, or clinic. If you will be using tobramicina IBI at home, a health care provider will teach you how to use it. Be sure you understand how to use tobramicina IBI. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

Do not use tobramicina IBI if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

Ask your health care provider any questions you may have about how to use tobramicina IBI.

How do I store tobramicina IBI (tobramicina solfato)?

Tobramicina IBI is usually handled and stored by a health care provider. If you are using tobramicina IBI at home, store it as directed by your pharmacist or health care provider. Keep tobramycin, as well as syringes and needles, out of the reach of children and away from pets.

Precautions & warnings

What should I know before using tobramicina IBI (tobramicina solfato)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of tobramicina IBI or other medications.
  • You have any other illnesses, disorders, or medical conditions.

Tobramicina IBI only works against bacteria; it does not treat viral infections (e.g., the common cold).

Drinking extra fluids while you are using tobramicina IBI is recommended. Check with your doctor for instructions.

Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

Be sure to use tobramicina IBI for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

Long-term or repeated use of tobramicina IBI may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

Some of these products contain sulfites. Sulfites may cause an allergic reaction in some patients (e.g., asthma patients). If you have ever had an allergic reaction to sulfites, ask your pharmacist if your product has sulfites in it.

Tell your doctor or dentist that you take tobramicina IBI before you receive any medical or dental care, emergency care, or surgery.

Lab tests, including kidney function, hearing tests, blood electrolyte levels, and tobramycin levels, may be performed while you use tobramycin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Use tobramicina IBI with caution in the elderly; they may be more sensitive to its effects, especially kidney or hearing problems.

Tobramicina IBI should be used with extreme caution in children younger than 10 years old; safety and effectiveness in these children have not been confirmed.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using this medication during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication.

Side effects

What side effects can occur from tobramicina IBI (tobramicina solfato)?

Check with your doctor if any of these most common side effects persist or become bothersome:

  • Diarrhea
  • Headache
  • Nausea
  • Pain, swelling, or redness at the injection site
  • Vomiting

Seek medical attention right away if any of these severe side effects occur:

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
  • Clumsiness
  • Confusion
  • Decreased hearing or other hearing changes
  • Decreased urination
  • Dizziness or light-headedness
  • Feeling of a whirling motion
  • Fever, chills, or persistent sore throat
  • Hearing loss
  • Loss of coordination
  • Muscle weakness
  • Numbness or tingling
  • Red, swollen, blistered, or peeling skin
  • Ringing or roaring in the ears
  • Seizures
  • Severe or persistent diarrhea
  • Stomach pain or cramps
  • Unusual bruising or bleeding
  • Vaginal irritation or discharge

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with tobramicina IBI (tobramicina solfato)?

Tobramicina IBI may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with your drug, such as:

  • Cephaloridine, cephalosporins (e.g., ceftizoxime), cisplatin, colistin, cyclosporine, fludarabine, loop diuretics (e.g., furosemide, ethacrynic acid), methoxyflurane, nitrosoureas (e.g., carmustine), nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen), polymyxin B, vancomycin, or viomycin because they may increase the risk of tobramicina IBI ‘s side effects, including increased risk of kidney or hearing loss.
  • Beta-lactam antibiotics (e.g., penicillin, imipenem, ceftizoxime) because they may decrease tobramicina IBI ‘s effectiveness.
  • Nondepolarizing muscle relaxants (e.g., atracurium) or succinylcholine because the risk of their side effects may be increased by tobramicina IBI.

Does food or alcohol interact with tobramicina IBI (tobramicina solfato)?

Tobramicina IBI may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with tobramicina IBI (tobramicina solfato)?

Tobramicina IBI may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Myasthenia gravis (a condition in which the muscles become progressively paralyzed)
  • Parkinson disease
  • Hearing problems
  • Nerve problems
  • Kidney problems
  • Severe or extensive burns
  • Dehydrated

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using tobramicina IBI (tobramicina solfato).

What is the dose of tobramicina IBI (tobramicina solfato) for an adult?

Bacterial Infections

The recommended dose is 3-6 mg/kg/day IV/IM divided q8hr OR.

The recommended dose is 4-7 mg/kg/dose IV/IM qDay.

Renal Impairment

  • Clcr >60 mL/min: q8hr
  • Clcr 40-60 mL/min: q12hr
  • Clcr 20-40 mL/min: q24hr
  • Clcr 10-20 mL/min: q48hr
  • Clcr <10 mL/min: q72hr

Following dialysis in ESRD

Life-threatening infection:

The recommended dose is 8-10 mcg/mL.

Serious infection:

The recommended dose is 6-8 mcg/mL.

UTIs:

The recommended dose is 4-6 mcg/mL.

Synergy for infections caused by gram-positive organisms:

The recommended dose is 3-5 mcg/mL.

What is the dose of tobramicina IBI (tobramicina solfato) for a child?

Cystic Fibrosis

IV/IM: The recommended dose is 2.5-3.3 mg/kg q6-8hr

Neonates

<30 week gestation

  • <28 days old: The recommended dose is 2.5 mg/kg IV/IM qDay.
  • ≥28 days old: The recommended dose is 3 mg/kg IV/IM qDay.

30-36 week gestation

  • <14 days old: The recommended dose is 3 mg/kg IV/IM qDay.
  • ≥14 days old: The recommended dose is 5 mg/kg/day IV/IM divided q12hr.

>37 week gestation

  • <7 days old: The recommended dose is 5 mg/kg/day IV/IM divided q12hr.
  • ≥7 days old: The recommended dose is 7.5 mg/kg/day IV/IM divided q8hr.

Bacterial Infection

<5 years old: The recommended dose is 2.5 mg/kg/dose IV/IM q8hr.

≥5 years old: The recommended dose is 2-2.5 mg/kg/dose IV/IM q8hr.

Hemodialysis:

The recommended dose is 1.25-1.75 mg/kg/dose postdialysis.

How is tobramicina IBI (tobramicina solfato) available?

Tobramicina IBI is available in the following dosage forms and strengths:

  • Tobramicina IBI 150 mg / 2 ml injection

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of tobramicina IBI, use it as soon as possible. Check with your doctor or pharmacist for instructions on scheduling other doses.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: May 16, 2017 | Last Modified: May 16, 2017

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