Generic Name: Tetrahydrozoline Brand Name(s): Generics only. No brands available.


What is tetrahydrozoline used for?

Tetrahydrozoline is commonly used for relieving redness due to minor eye irritation.

Tetrahydrozoline eye drops are a decongestant. It works by constricting swollen blood vessels in the eye, which reduces redness. Irritants cause blood vessels to swell.

How should I take tetrahydrozoline?

Use tetrahydrozoline eye drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Tetrahydrozoline eye drops are for use in the eye only. Avoid contact with mucous membranes.

If you wear contact lenses, remove them before using tetrahydrozoline eye drops.

To use tetrahydrozoline eye drops, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye and continue to apply pressure for 1 to 2 minutes after using the medicine. Do not blink.

Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye.

Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye.

Keep the container tightly closed.

Do not use tetrahydrozoline eye drops if solution changes color or becomes cloudy.

How do I store tetrahydrozoline?

Tetrahydrozoline is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store tetrahydrozoline in the bathroom or the freezer. There may be different brands of tetrahydrozoline that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush tetrahydrozoline down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using tetrahydrozoline?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of tetrahydrozoline or other medications.
  • You have any other illnesses, disorders, or medical conditions.
  • You are taking furazolidone or have taken a monoamine oxidase (MAO) inhibitor (e.g., phenelzine) within the last 14 days.
  • You have narrow-angle glaucoma, an overactive thyroid, or high blood pressure.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using tetrahydrozoline during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking tetrahydrozoline.

Side effects

What side effects can occur from tetrahydrozoline?

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist or become bothersome:

  • Blurring, tearing, or stinging of the eye
  • Dilation of pupils

Seek medical attention right away if any of these severe side effects occur:

  • Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
  • Change in vision
  • Continued redness or irritation of the eye
  • Eye pain
  • Headache

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with tetrahydrozoline?

Tetrahydrozoline may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products that may interact with this drug are:

  • Furazolidone and MAO inhibitors (e.g., phenelzine) because side effects, such as headache, high blood pressure, and elevated body temperature, may occur.
  • Tricyclic antidepressants (e.g., amitriptyline) because they may decrease tetrahydrozoline eye drops’s effectiveness.
  • Bromocriptine or catechol-O-methyltransferase (COMT) inhibitors (e.g., tolcapone, St. John’s wort) because their actions and side effects may be increased by tetrahydrozoline eye drops.

Does food or alcohol interact with tetrahydrozoline?

Tetrahydrozoline may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with tetrahydrozoline?

Tetrahydrozoline may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using tetrahydrozoline.

What is the dose of tetrahydrozoline for an adult?

Usual Adult Dose for Eye Dryness/Redness

Instill 1-2 drops into each affected eye 1-4 times a day as needed.

What is the dose of Tetrahydrozoline for a child?

Usual Pediatric Dose for Eye Dryness/Redness

<6 years: Consult a physician before using.

6-18 years: Instill 1-2 drops into each affected eye 1-4 times a day as needed.

How is tetrahydrozoline available?

Tetrahydrozoline is available in the following dosage forms and strengths:

  • Eye drops 0,05%

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of tetrahydrozoline eye drops and you are using it regularly, use it as soon as possible. If it is much more than 1 hour since your missed dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Hello Health Group does not provide medical advice, diagnosis or treatment.

msBahasa Malaysia

Review Date: August 23, 2017 | Last Modified: September 2, 2017

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