Sulfanilamide

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Generic Name: Sulfanilamide Brand Name(s): Generics only. No brands available.

Uses

What is Sulfanilamide used for?

Sulfanilamide is used to treat vaginal yeast infections. Sulfanilamide reduces vaginal burning, itching, and discharge that may occur with this condition. This medication is known as a sulfonamide antifungal. It works by stopping the growth of yeast (fungus) that causes the infection.

How should I take Sulfanilamide?

This medication is for vaginal use only. Wash your hands before and after use. Use sulfanilamide usually once or twice daily or as directed by your doctor. Lie on your back with your knees toward your chest. Insert one applicator full of cream into the vagina as far as it will comfortably go. Slowly press the plunger of the applicator all the way in to apply the cream. If you have itching/burning around the outside of the vagina (vulva), apply some cream to that area as well. Consult your doctor or pharmacist if you have any questions on the use of this medication.

Continue to use this medication every day for the full time prescribed, even if symptoms disappear after a few days or if your menstrual period starts. Stopping the medication too soon may allow the yeast infection to return.

Do not use tampons while using this medication. Unscented sanitary napkins may be used for your menstrual period or to protect your clothing from leakage of the medication.

Tell your doctor if your condition persists or returns within 2 months after completing the treatment. Also, tell your doctor right away if you have fever, chills, flu-like symptoms, or stomach/abdominal pain. This may mean you have a more serious infection and may need another treatment.

How do I store Sulfanilamide?

Sulfanilamide is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Sulfanilamide in the bathroom or the freezer. There may be different brands of Sulfanilamide that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Sulfanilamide down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Sulfanilamide?

Before using sulfanilamide, tell your doctor or pharmacist if you are allergic to it; or to other sulfa drugs (such as sulfamethoxazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, immune system problems (such as HIV infection), 4 or more vaginal yeast infections a year, blood disorders (such as anemia), certain metabolic disorders (G6PD deficiency, porphyria).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Ask your doctor whether you can have sexual intercourse while using this product. This product may weaken rubber products (such as latex condoms, diaphragms, cervical caps) and lead to failure. This can result in pregnancy. Therefore, do not use these products during treatment with this medication. Consult your doctor about other forms of barrier protection/birth control (such as polyurethane condoms) during this time.

During pregnancy, this medication should be used only when clearly needed. If you are pregnant, follow your doctor’s instructions on how to use the applicator to insert this medication. This medication should not be used near the expected delivery date because of possible harm to the unborn baby. Discuss the risks and benefits with your doctor.

This medication passes into breast milk but is unlikely to harm a healthy nursing infant. However, ill or premature infants may be at higher risk for undesirable effects. Consult your doctor before breast-feeding.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Sulfanilamide during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Sulfanilamide. Sulfanilamide is pregnancy risk category C according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Sulfanilamide?

Tell your doctor right away if any of these unlikely but serious side effects occur: new or increased burning/itching/discomfort in the vaginal area.

Tell your doctor right away if any of these rare but seriousunusual tiredness, dark urine, easy bruising/bleeding.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Sulfanilamide?

Sulfanilamide may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Sulfanilamide?

Sulfanilamide may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Sulfanilamide?

Sulfanilamide may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this Sulfanilamide.

What is the dose of Sulfanilamide for an adult?

Usual Adult Dose for Vaginal Candidiasis

Cream: 1 applicatorful (about 6 g) intravaginally once or twice a day for 30 days

Precautions

Because sulfanilamide topical is absorbed from the vaginal mucosa, the usual precautions for oral sulfonamides apply. Patients should be observed for skin rash or evidence of systemic toxicity. Therapy should be discontinued if local or systemic manifestations of sulfonamide toxicity or sensitivity occur.

Patients should be advised to discontinue sulfanilamide topical if unusual local itching and burning occur, or other unusual symptoms develop. The medication should not be restarted without further consultation.

Vaginal applicators or inserters should be used with caution after the seventh month of pregnancy.

Other Comments

Symptoms should improve within a few days but therapy should be continued for 30 days.

For hygienic purposes, douching with a suitable solution may be recommended before insertion.

What is the dose of Sulfanilamide for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Sulfanilamide available?

Sulfanilamide is available in the following dosage forms and strengths:

  • Vaginal cream,
  • Vaginal suppository.

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Sulfanilamide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Review Date: June 1, 2018 | Last Modified: June 1, 2018

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