Singulair

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Generic Name: Singulair Brand Name(s): Generics only. No brands available.

Uses

What is Singulair® (montelukast) used for?

Singulair® is a leukotriene inhibitor. They are chemicals your body releases when you breathe in an allergen (such as pollen). These chemicals cause swelling in your lungs and tightening of the muscles around your airways, which can result in asthma symptoms.

Singulair® is used to prevent asthma attacks in adults and children as young as 12 months old. Singulair® is also used to prevent exercise-induced bronchospasm in adults and children who are at least 6 years old.

Singulair® is also used to treat symptoms of year-round (perennial) allergies in adults and children who are at least 6 months old. It is also used to treat symptoms of seasonal allergies in adults and children who are at least 2 years old.

Singulair is also used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs) in adults and teenagers who are at least 15 years old and are not already taking this medicine for other conditions.

How should I take Singulair® (montelukast)?

Take Singulair® exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Singulair® is usually taken once daily in the evening for prevention of asthma or allergy symptoms. For exercise-induced bronchoconstriction, take a single dose at least 2 hours before you exercise, and do not take another dose for at least 24 hours. Follow your doctor’s instructions.

Singulair® is not a rescue medicine. It will not work fast enough to treat an asthma attack. Use only a fast acting inhalation medicine for an asthma attack. Tell your doctor if it seems like your asthma medications don’t work as well.

Swallow the regular tablet whole, with a glass of water.

The Singulair® chewable tablet must be chewed completely before you swallow it.

The oral granules can be placed directly into the mouth and swallowed, or mixed with a spoonful of applesauce, mashed carrots, rice, or ice cream. Oral granules can also be mixed with 1 teaspoon of baby formula or breast milk. Do not use any other type of liquid for mixing the granules. Other liquids can be taken before or after taking the medicine.

After opening or mixing the oral granules, you must use them within 15 minutes. Do not save an open packet or mixed medicine for later use.

It may take up to several weeks before your symptoms improve. Keep using Singulair® as directed and tell your doctor if your symptoms do not improve after several weeks of treatment.

If you also take a steroid asthma medicine, do not stop using it suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

How do I store Singulair® (montelukast)?

Singulair® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Singulair® in the bathroom or the freezer. There may be different brands of Singulair® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Singulair® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Singulair® (montelukast)?

Before using this drug, tell your doctor if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • You have allergy with any of active or inactive ingredients of Singulair® or other medications.
  • You have any other illnesses, disorders, or medical conditions.

The chewable tablet may contain phenylalanine. Talk to your doctor before using this form of Singulair® if you have phenylketonuria (PKU).

Singulair® is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether Singulair® passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Avoid situations or activities that may trigger an asthma attack. If your asthma symptoms get worse when you take aspirin, avoid taking aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs) while you are taking Singulair®. NSAIDs include ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Singulair® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Singulair®. Singulair® is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Singulair® (montelukast)?

Common side effects may include:

  • Stomach pain
  • Diarrhea
  • Fever or other flu symptoms
  • Cold symptoms such as stuffy nose, sinus pain, cough, sore throat
  • Headache
  • Bed-wetting or loss of bladder control in children

Call your doctor at once if you have:

  • Unusual changes in mood or behavior
  • Skin rash, bruising, severe tingling, numbness, pain, muscle weakness
  • Ear pain, swelling, or warmth
  • Severe skin reaction – fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling

Get emergency medical help if you have signs of an allergic reaction to Singulair®: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Singulair® (montelukast)?

Singulair® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Singulair® (montelukast)?

Singulair® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Singulair® (montelukast)?

Singulair® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Health conditions that may interact with this drug are:

  • Asthma
  • A history of severe allergic reaction to aspirin

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Singulair® (montelukast).

What is the dose of Singulair® (montelukast) for an adult?

Asthma

Singulair® should be taken once daily in the evening.

For adults and adolescents 15 years of age and older: one 10-mg tablet.

Exercise-Induced Bronchoconstriction (EIB)

For prevention of EIB, a single dose of Singulair® should be taken at least 2 hours before exercise.

For adults and adolescents 15 years of age and older: one 10-mg tablet.

Allergic Rhinitis

For allergic rhinitis, Singulair® should be taken once daily. Efficacy was demonstrated for seasonal allergic rhinitis when montelukast was administered in the morning or the evening without regard to time of food ingestion. The time of administration may be individualized to suit patient needs.

For the treatment of symptoms of seasonal allergic rhinitis for adults and adolescents 15 years of age and older: one 10-mg tablet.

For the treatment of symptoms of perennial allergic rhinitis for adults and adolescents 15 years of age and older: one 10-mg tablet.

Asthma and Allergic Rhinitis

Patients with both asthma and allergic rhinitis should take only one Singulair® dose daily in the evening.

What is the dose of Singulair® (montelukast) for a child?

Asthma

Singulair® should be taken once daily in the evening. The following doses are recommended:

  • For adolescents 15 years of age and older: one 10-mg tablet.
  • For pediatric patients 6 to 14 years of age: one 5-mg chewable tablet.
  • For pediatric patients 2 to 5 years of age: one 4-mg chewable tablet or one packet of 4-mg oral granules.
  • For pediatric patients 12 to 23 months of age: one packet of 4-mg oral granules.
  • Safety and effectiveness in pediatric patients less than 12 months of age with asthma have not been established.

Exercise-Induced Bronchoconstriction (EIB)

For prevention of EIB, a single dose of Singulair® should be taken at least 2 hours before exercise. The following doses are recommended:

  • For adolescents 15 years of age and older: one 10-mg tablet.
  • For pediatric patients 6 to 14 years of age: one 5-mg chewable tablet.

Allergic Rhinitis

For allergic rhinitis, Singulair® should be taken once daily. Efficacy was demonstrated for seasonal allergic rhinitis when montelukast was administered in the morning or the evening without regard to time of food ingestion. The time of administration may be individualized to suit patient needs.

The following doses for the treatment of symptoms of seasonal allergic rhinitis are recommended:

  • For adolescents 15 years of age and older: one 10-mg tablet.
  • For pediatric patients 6 to 14 years of age: one 5-mg chewable tablet.
  • For pediatric patients 2 to 5 years of age: one 4-mg chewable tablet or one packet of 4-mg oral granules.
  • Safety and effectiveness in pediatric patients younger than 2 years of age with seasonal allergic rhinitis have not been established.

The following doses for the treatment of symptoms of perennial allergic rhinitis are recommended:

  • For adolescents 15 years of age and older: one 10-mg tablet.
  • For pediatric patients 6 to 14 years of age: one 5-mg chewable tablet.
  • For pediatric patients 2 to 5 years of age: one 4-mg chewable tablet or one packet of 4-mg oral granules.
  • For pediatric patients 6 to 23 months of age: one packet of 4-mg oral granules.
  • Safety and effectiveness in pediatric patients younger than 6 months of age with perennial allergic rhinitis have not been established.

Asthma and Allergic Rhinitis

Patients with both asthma and allergic rhinitis should take only one Singulair® dose daily in the evening.

How is Singulair® (montelukast) available?

Singulair® is available in the following dosage forms and strengths:

  • Tablets, chewable tablets, oral granules: montelukast sodium 4mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Singulair®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: July 19, 2017 | Last Modified: July 19, 2017

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