Generic Name: Sevorane Brand Name(s): Generics only. No brands available.

Uses

What is Sevorane ® (sevoflurane) used for?

Sevoflurane is an anesthetic. It works by decreasing activity in the central nervous system, which causes loss of consciousness. It is commonly used before and during surgery.

How should I take Sevorane ® (sevoflurane)?

Sevoflurane is usually administered by your doctor or other health care provider during surgery.

How do I store Sevorane ® (sevoflurane)?

Sevorane ® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Sevorane ® in the bathroom or the freezer. There may be different brands of Sevorane ® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Sevorane ® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Sevorane ® (sevoflurane)?

Before using this drug, tell your doctor if:

  • You are pregnant, planning to become pregnant, or are breastfeeding.
  • You are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.
  • You have allergies to medicines, foods, or other substances.

Sevoflurane will cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to sevoflurane. Using sevoflurane alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.

Is it safe during pregnancy or breastfeeding?

Pregnancy

If you become pregnant while taking sevoflurane, discuss with your doctor the benefits and risks of using sevoflurane during pregnancy.

Breastfeeding

It is unknown if sevoflurane is excreted in breast milk. If you are or will be breastfeeding while you are using sevoflurane, check with your doctor or pharmacist to discuss the risks to your baby.

Side effects

What side effects can occur from Sevorane ® (sevoflurane)?

Some side effects can occur when using this drug, such as:

  • Agitation
  • Dizziness
  • Drowsiness
  • Increased cough
  • Increased saliva
  • Lightheadedness
  • Nausea
  • Shivering
  • Vomiting

Seek medical attention right away if any of these severe side effects occur:

  • Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
  • Chills
  • Fast, slow, or irregular heartbeat
  • Fever
  • Seizures
  • Unusual change in amount or urine
  • Yellowing of the skin or eyes

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Sevorane ® (sevoflurane)?

Sevorane ® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug, including:

Does food or alcohol interact with Sevorane ® (sevoflurane)?

Sevorane ® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Sevorane ® (sevoflurane)?

Sevorane ® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Liver problems
  • Kidney problems
  • Seizures

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Sevorane ® (sevoflurane).

What is the dose of Sevorane ® (sevoflurane) for an adult?

Anesthesia

  • 12-25 years, 2.6% in oxygen or 1.4% with 65% N2O/35% oxygen
  • 25-40 years, 2.1% in oxygen or 1.1% with 65% N2O/35% oxygen
  • 40-60 years, 1.7% in oxygen or 0.9% with 65% N2O/35% oxygen
  • 60-80 years, 1.4% in oxygen or 0.7% with 65% N2O/35% oxygen

What is the dose of Sevorane ® (sevoflurane) for a child?

Anesthesia

  • < 1month full term neonate, 3.3% in oxygen
  • 1-6 months, 3% in oxygen
  • 6 months to <3 years, 2.8% in oxygen or 2 % with 65% N2O/35% oxygen
  • 3-12 years, 2.5% in oxygen or 2.5 % with 65% N2O/35% oxygen

How is Sevorane ® (sevoflurane) available?

Sevorane ® is available in the following dosage forms and strengths:

  • Evaporate 100% solution: 250 ml bottle

What should I do in case of an emergency or overdose?

In the event of overdosage, or what may appear to be overdosage, the following action should be taken: discontinue administration of Sevoflurane, maintain a patent airway, initiate assisted or controlled ventilation with oxygen, and maintain adequate cardiovascular function.

What should I do if I miss a dose?

If you miss a dose of Sevorane ®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Review Date: February 10, 2017 | Last Modified: February 10, 2017

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